Huberman Lab

Using Caffeine to Optimize Mental & Physical Performance

Huberman Lab with Andrew Huberman

Summary

Comprehensive guide to caffeine use including mechanisms, optimal timing, dosing strategies, and how to avoid tolerance.

Key Points

  • Caffeine blocks adenosine receptors
  • 1-3mg/kg body weight is effective dose
  • Delay morning caffeine 90-120 min after waking
  • Avoid after 2pm for sleep quality
  • Tolerance develops - consider cycling
  • Withdrawal symptoms peak at 24-48 hours

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