Low-level laser (light) therapy (LLLT) for treatment of hair loss

Avci P, Gupta GK, Clark J, Wikonkal N, Hamblin MR (2013) Lasers in Surgery and Medicine

Key Takeaway

Review demonstrating red light therapy stimulates cellular activity in skin and hair follicles, with FDA-cleared devices showing efficacy for hair growth.

Summary

While focused on hair loss treatment, this review provides valuable insights into how red light affects skin and cellular metabolism broadly.

The paper reviews the mechanisms by which red and NIR light stimulate cellular activity through mitochondrial absorption and increased ATP production. Several FDA-cleared devices for hair growth demonstrate that red light can meaningfully affect biological processes in the skin.

The findings support the use of red light for skin health applications, including collagen production and wound healing.

Methods

  • Review of LLLT mechanisms
  • Analysis of clinical trials for hair growth
  • FDA device clearance data
  • Assessment of safety profile

Key Results

  • Red light (630-670nm) stimulates cellular metabolism
  • Hair follicle activity increases with treatment
  • FDA-cleared devices show statistical improvement
  • Good safety profile with minimal side effects

Limitations

  • Review focused on hair, not skin broadly
  • Device quality and parameters vary
  • Long-term maintenance effects unknown
  • Optimal treatment protocols not standardized

Related Interventions

Source

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DOI: 10.1002/lsm.22170