Is this medical advice?
No. YouBoost is an educational resource, not a substitute for professional medical advice. The information here is intended to help you understand what the research says about various interventions, but you should always consult a qualified healthcare provider before starting any new supplement, treatment, or protocol.
We don't know your medical history, current medications, or individual circumstances. What works for one person may be harmful for another.
How do you rate evidence?
We use a three-tier system:
- A (Strong) - Multiple high-quality randomized controlled trials (RCTs), meta-analyses, or systematic reviews showing consistent, clinically meaningful effects
- B (Moderate) - Some RCTs showing positive effects, or consistent observational data with plausible mechanisms
- C (Preliminary) - Limited human research, primarily animal/cell studies, or mixed results that warrant caution
See our full methodology page for detailed criteria.
How do you select interventions?
We cover interventions that meet these criteria:
- Have human research - At minimum, some peer-reviewed studies in humans (not just animal or cell studies)
- Are actionable - You can actually implement them (not just theoretical mechanisms)
- Have measurable outcomes - Effects that can be tracked or quantified
- Are relevant to optimization - Related to performance, health, recovery, or longevity
We don't cover every supplement or biohack. We focus on interventions with enough research to say something meaningful about.
Why do some interventions have low evidence ratings?
A low rating doesn't mean something doesn't work. It means we don't have enough high-quality evidence to be confident it works.
Many promising interventions are rated C because:
- Research is preliminary (animal studies, small trials)
- Studies show mixed results
- Mechanisms are plausible but unproven in humans
A C-rated intervention might be worth trying, but you should know you're taking a bet on incomplete information.
Do you have conflicts of interest?
We use Amazon affiliate links for product recommendations, which means we earn a small commission if you purchase through those links. This doesn't affect our evidence ratings or editorial decisions.
We don't accept payment from supplement companies, and we don't adjust ratings based on commercial relationships.
How often is the content updated?
We update interventions when significant new research is published. Evidence ratings can change as new studies emerge.
Each intervention page shows a "date added" field. Major updates are noted in the content itself.
Can I suggest an intervention?
Yes. If there's an intervention you'd like us to cover, reach out via our contact page. We prioritize suggestions based on the quality of available research and relevance to our audience.
Why isn't [intervention] rated higher?
Our ratings reflect the current state of peer-reviewed research, not popularity or anecdotal reports. An intervention might have strong testimonials but weak clinical evidence.
If you think we've missed important studies, let us know. We're happy to revisit ratings when presented with quality research we may have overlooked.