Key Takeaway
Shilajit supplementation dose-dependently preserved bone mineral density and reduced markers of oxidative stress and inflammation in postmenopausal women with osteopenia over 48 weeks.
Summary
This randomized, double-blind, placebo-controlled trial investigated the effects of shilajit extract on bone mineral density in postmenopausal women diagnosed with osteopenia. Participants were randomized to receive either placebo or one of two doses of shilajit extract over a 48-week period.
The study found that shilajit supplementation produced dose-dependent improvements in bone mineral density at the lumbar spine and hip, while the placebo group continued to lose bone mass. Markers of oxidative stress and inflammation were significantly reduced in the shilajit groups compared to placebo.
These findings suggest that shilajit may help preserve bone health in postmenopausal women by reducing the oxidative stress and chronic inflammation that contribute to bone resorption. The dose-dependent response strengthens the case for a causal relationship between shilajit supplementation and bone-protective effects.