Huberman Lab

Healing From Grief & Loss | Dr. Mary-Frances O'Connor

Huberman Lab with Dr. Mary-Frances O'Connor 2025-06-02

Summary

Dr. Mary-Frances O'Connor discusses the neuroscience of grief and loss, including how the brain processes attachment and practical approaches to healing.

Key Points

  • Grief is a learning process for the brain
  • Attachment bonds persist neurologically
  • Time and processing aid healing
  • Physical health impacts grief recovery
  • Social support is protective
  • Professional help when needed

Key Moments

Grief rewires the brain like addiction

Dr. O'Connor explains how grief shares neural circuitry with addiction - the brain's mapping of a loved one becomes disrupted, and the longing to be reunited activates the same reward pathways as substance cravings, explaining why grief can feel like withdrawal.

"I loosely define addiction as a progressive narrowing of the things that bring you pleasure."
Grief And Loss

Disordered grief affects one in ten and raises medical risk

O'Connor describes how about 10% of bereaved people develop disordered grieving where time passing doesn't help, and how grief significantly increases risk of heart attack, immune dysfunction, and other medical conditions for both the grieving person and those around them.

"We do know for the one out of ten who develop disordered grieving, who really are not showing any changes over time, even though time is passing, those people need help."

Break the rumination cycle by simply getting up and walking

O'Connor shares a practical tool for grief rumination - when you catch yourself in repetitive questioning loops, literally get up and walk outside. The physical shift alone changes thought patterns, and the key question is not whether a thought is true but whether it is helpful.

"If I realize, oh, I'm doing the rumination thing again, literally, I just need to get up and walk outside, right? Just that shift alone can help to change my thought patterns."

Progressive muscle relaxation beats mindfulness for grief

A study comparing mindfulness training to progressive muscle relaxation in widows and widowers found that while both helped, progressive muscle relaxation was even more effective for grief management.

"It's, you know, you can go online. There's really easy instructions. It's often done with a sort of guided audio to help you figure out. But the important part is also feeling what's the difference between my clenched fist and my relaxed fist. Oh, gosh, I didn't even realize I had so much muscle tension, right? So what's fascinating is people told us in any situation, I'm in the grocery store, I'm in a work meeting, I'm trying to fall asleep, I can use this tool now to help my body to get into a different state. And that helps my grief. Now, mindfulness training was effective, but not as effective as I said. And I think some of this is that we have, you know, grieving is a form of learning. I'm not kidding about that. Your brain is busy while you are grieving. And it might not be the right time to take up a new practice that requires a lot of concentration. If you do mindfulness, it can be very helpful. Anyway, the upshot of all that is, on the one hand, it's not that we have to deal with emotions because they are an output. We have to deal with our demands and our resources and developing a whole toolkit of ways to think about adapting in our life now. On the other hand, even specifically for waves of grief, having a toolkit of what to do with those emotions, I think you described it beautifully, Andrew, that we do have the capacity for suppression. And if you are about to walk into a pitch meeting, suppression is probably the way to go in that moment where suddenly your deceased child has popped into your head and thinking, I am not going to think about this right now. I am completely going to pretend this has not happened, and I'm going to do this pitch, right? But if it's your only strategy, then you don't have the learning process going on, right? That at another moment, you might be looking through a photo album and just be overcome with tears, but over time realize, I can't stay in that puddle either. When I'm doing this, I need to, you know, if it was me, I need to text my sister and tell her, you know, I'm looking at photos of mom, and this is what I'm thinking about. And she'll text me some funny story about mom or even just say, oh man, I feel ya. And if my sister isn't available, then I'll text my best friend, right? Because in that moment, it is important to have that puddle. It's also important to know how to get out of the puddle again. And so this is really a process of learning. How do I cope with these waves of grief? It's like being a basketball player. One possession after another after another."

Featured Experts