Mastering Nutrition

Aging is best explained by declining mitochondrial function over time.

Mastering Nutrition with Chris Masterjohn 2025-12-09

Summary

Chris Masterjohn makes the case that aging is fundamentally driven by declining mitochondrial function. He reviews evidence linking mitochondrial deterioration to the hallmarks of aging and discusses nutritional and lifestyle strategies to support mitochondrial health throughout the lifespan.

Key Points

  • Mitochondrial decline is a central driver of the aging process
  • Oxidative damage accumulates in mitochondrial DNA over time
  • NAD+ depletion contributes to age-related mitochondrial dysfunction
  • Nutritional strategies can support mitochondrial biogenesis and function
  • Key nutrients for mitochondrial health include CoQ10, B vitamins, and magnesium

Related Interventions

Featured Experts