FoundMyFitness

#050 NAD+ in Aging: Role of Nicotinamide Riboside and Nicotinamide Mononucleotide

FoundMyFitness with Rhonda Patrick 2019-11-13

Summary

Rhonda Patrick explores NAD+ in aging and the role of nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) as precursors. Covers the science of NAD+ decline with age and supplementation strategies.

Key Points

  • NAD+ declines with age
  • NR and NMN as NAD+ precursors
  • Comparison of different NAD+ boosters
  • Mitochondrial function and aging
  • Current research findings and limitations

Key Moments

NMN mitigates age-related decline in mice

Rhonda Patrick's deep dive on NAD precursors. Long-term NMN in mice improved muscle function, mitochondria, and energy metabolism.

"Dietary administration of nicotinamide mononucleotide mitigated the age-associated physiological decline in mice with an accelerated aging phenotype."

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