The Human Upgrade
Ben Greenfield Life
Huberman Lab
The Proof with Simon Hill

Boost Your Mitochondria

12 episodes

Red light, cold exposure, zone 2 cardio, and NAD+ precursors. The science of cellular energy production and why mitochondrial health is the foundation of everything.

Red light, cold exposure, zone 2 cardio, and NAD+ precursors. The science of cellular energy production and why mitochondrial health is the foundation of everything.

Episodes

1
The Human Upgrade
The WATER Hack That Boosts Mitochondria by 11%! : 1343
The Human Upgrade Dave Asprey 2025-10-10

Dave Asprey explores mitochondrial health and strategies for optimizing cellular energy.

2
Ben Greenfield Life
The TRUTH About What's *Really* Causing Your Fatigue & The "Root Cause" Protocol to Fix It, With Morley Robbins.
Ben Greenfield Life Ben Greenfield 2025-11-22

Ben Greenfield investigates the real causes of fatigue beyond sleep deprivation, covering mitochondrial function, hormones, and lifestyle factors.

3
Huberman Lab
How to Use Exercise to Improve Your Brain’s Health, Longevity & Performance
Huberman Lab Andrew Huberman 2025-01-06

Andrew Huberman explains how different forms of exercise impact brain health and cognitive performance in both the short and long term. He covers how arousal and alertness from ...

4
Huberman Lab
Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation | Dr. Casey Means
Huberman Lab Dr. Casey Means 2024-05-06

Dr. Casey Means, a Stanford-trained physician and author of 'Good Energy,' explains how metabolic dysfunction is the root cause of most chronic disease in America, with 93% of a...

5
The Human Upgrade
This Brain Trick Feels Like Cheating - Microglia and Brain Health
The Human Upgrade Dr. David Perlmutter 2026-01-22

Dr. David Perlmutter, board-certified neurologist and six-time NYT bestselling author, explains how mitochondrial health inside microglia (brain immune cells) influences cogniti...

6
The Proof with Simon Hill
Lactate: The Key to Metabolic Health, Mitochondria, and Longevity | Dr Iñigo San Millán
The Proof with Simon Hill Inigo San Millan 2025-10-06

In this follow-up conversation, Simon Hill and Dr. Inigo San Millan take a deep dive into lactate -- debunking the long-held myth that it is a toxic waste product and revealing ...

7
Ben Greenfield Life
Peptides, Biologics & Small Molecules You've *Never Heard Of* For Sleep, Mitochondria, Kidney Health & More, With Jim LaValle.
Ben Greenfield Life Jim LaValle 2026-01-22

Clinical pharmacist Jim LaValle joins Ben Greenfield to discuss innovative approaches to health, performance, and longevity. They cover peptides and small molecules for mitochon...

8
FoundMyFitness
#050 NAD+ in Aging: Role of Nicotinamide Riboside and Nicotinamide Mononucleotide
FoundMyFitness Rhonda Patrick 2019-11-13

Rhonda Patrick explores NAD+ in aging and the role of nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) as precursors. Covers the science of NAD+ decline with age...

9
FoundMyFitness
#060 Dr. Giselle Petzinger on Exercise for Parkinson's Disease
FoundMyFitness Dr. Giselle Petzinger 2020-10-14

High-intensity exercise at 80-85% max heart rate, 3x weekly, may slow Parkinson's progression by promoting neuroplasticity. Skill-based activities like boxing, tai chi, and tang...

10
Live Well Be Well with Sarah Ann Macklin | Health, Lifestyle, Nutrition
Zone 2 Training Explained: The Single Best Workout for Your Mitochondria | Dr. Inigo San Millan
Live Well Be Well with Sarah Ann Macklin | Health, Lifestyle, Nutrition Inigo San Millan 2025-11-19

Sarah Macklin interviews Dr. Inigo San Millan on why mitochondrial function represents the next frontier beyond VO2 max for understanding health and longevity. San Millan explai...

11
FoundMyFitness
#075 Intestinal Permeability: the Bacterial link to Aging, Brain Barrier Dysfunction & Metabolic Disorder
FoundMyFitness Rhonda Patrick 2022-05-31

Leaky gut drives chronic inflammation that accelerates aging, heart disease, and neurodegeneration. Learn which foods and habits damage your intestinal barrier, and the specific...

12
Dr. Jockers Functional Nutrition
The Melatonin, Mitochondria, Sex Hormones and Inflammation Connection!
Dr. Jockers Functional Nutrition David Jockers 2022-10-27

Dr. David Jockers reveals the surprising connections between melatonin, mitochondrial function, sex hormones, and inflammation. He explains how melatonin acts as a powerful mito...

Related Research

Markers of clinical and mitochondrial adaptation in response to moderate intensity continuous training: A systematic review and meta-analysis
Vabishchevich V, Smith RT, Bittel AJ (2026)
Across 14 studies (n=184), moderate-intensity continuous training significantly increased mitochondrial volume density (p<0.00001) and VO2max (p<0.0001), with modest gains in citrate synthase and MFN2, confirming Zone 2-type exercise drives meaningful mitochondrial adaptation.
Effects of photobiomodulation on multiple health outcomes: an umbrella review of randomized clinical trials.
Son Y, Lee H, Yu S, et al. (2025)
Umbrella review of 20 systematic reviews found photobiomodulation has significant benefits for pain reduction, functional recovery, wound healing, and inflammation, though evidence quality varies across outcomes.
Impact of different doses of cold water immersion on recovery from acute exercise-induced muscle damage
Wang H, et al. (2025)
Network meta-analysis of 55 RCTs found 10-15 min at 11-15°C optimal for reducing muscle soreness and damage markers.
High-intensity interval training and cardiorespiratory fitness in adults: An umbrella review of systematic reviews and meta-analyses.
Poon ET, Li H, Gibala MJ, et al. (2024)
HIIT produces large, consistent improvements in cardiorespiratory fitness across diverse adult populations, with effect sizes comparable to or greater than moderate-intensity continuous training.
The multifaceted benefits of passive heat therapies for extending the healthspan: A comprehensive review with a focus on Finnish sauna.
Laukkanen JA, Kunutsor SK (2024)
Passive heat therapies including sauna bathing are associated with reduced risk of cardiovascular disease, dementia, respiratory conditions, and all-cause mortality, with dose-response benefits at 4-7 sessions per week.
Photobiomodulation in the aging brain: a systematic review from animal models to humans.
Rodríguez-Fernández L, Zorzo C, Arias JL (2024)
Photobiomodulation demonstrates neuroprotective, anti-inflammatory, and mitochondrial-restoring effects in the aging brain, improving working memory, cognitive inhibition, and general cognition in both animal models and humans