Summary
Clinical pharmacist Jim LaValle joins Ben Greenfield to discuss innovative approaches to health, performance, and longevity. They cover peptides and small molecules for mitochondrial and kidney support, improving VO2 max, brain function, and sleep. LaValle explains his Metabolic Code test for identifying health bottlenecks.
The conversation explores peptides like KPV, BPC-157, and lorazotide for gut healing, and examines trends LaValle sees in high performers - including stress-driven hormone changes and subtle signs of inflammation. They discuss how personalized lab testing, wearable data, and smart supplementation can optimize performance and aging.
Key Points
- Peptides like KPV, BPC-157, and lorazotide can support gut healing
- The Metabolic Code test identifies major bottlenecks in health optimization
- Even high performers show stress-driven hormone changes and hidden inflammation
- Personalized lab testing combined with wearable data enables smarter supplementation
- Small molecules can support mitochondrial function and kidney health
- VO2 max improvement strategies discussed alongside brain function optimization
Key Moments
Vo2Max Training: How To
My son runs that company. There's a lot of different ways liposomes are made, man.
"My son runs that company. And I was looking for how to deliver small molecules or peptides in a solid state. And so I partnered with a pharmaceutical scientist and their liposomes. So everybody here's liposomes. There's a lot of different ways liposomes are made, man. It's like people can just pour some lethosin in with something and shake it up and say it's a liposome. This is a multi-layered liposome where the And so, whether it's a botanical, so I think you tried that in Duro2, which you really like that, which is like a botanical that we enhance the absorption of, and then your VO2 max goes up and you oxygenate your tissues. Or synapsin, which is a ginsinicide that's hard to get the absorb orally, but now when you get it to absorb, your brain gets clear. Yeah, and by the way, real quick, I'm glad you brought those two because I was just kind."
Thyroid Health Discussion
If you're finally ready to stop wasting time and money and start living the boundless life you know is possible, go to jointriumphcoaching.com right now and book your call. Once they're gone, they're gone.
"If you're finally ready to stop wasting time and money and start living the boundless life you know is possible, go to jointriumphcoaching.com right now and book your call. Spots are limited. Once they're gone, they're gone. Jointriumphcoaching.com. Do it now. You said that really fast. You said adrenal, thyroid, pancreas, then what? Cortisol, insulin, and thyroid hormone. Because your cortisol goes up, your thyroid conversion goes down."
Sodium Bicarbonate Discussion
You're probably a pre-diabetic and you haven't taken care of your insulin for a long time, then triad one. What the nephrologist does is gives you baking soda capsules.
"What the nephrologist does is gives you baking soda capsules."
Gut Microbiome: Probiotics
You're probably a pre-diabetic and you haven't taken care of your insulin for a long time, then triad one. What the nephrologist does is gives you baking soda capsules.
"They give you baking soda capsules so that you can suspend the time until you actually need to start dialysis. Because when you alkalineize the urine, well, your kidneys, it takes the pressure off the damage to them. But why are we waiting to teach people that they should try to keep that urine a little less acidic? Because, you know, A lot of people do not use the right probiotic because most probiotics die in your harsh stomach acid before they can do much good. And probiotics have so, if you go to PubMed, just thousands of research study on weight loss, increased energy, better sleep, beating that embarrassing post-meal bloat. Just Thrive makes a probiotic that is industry-leading, that survives your gut for better."
Collagen Discussion
Not only an energy bar, but the world's first ketone-powered energy bar.
"But I didn't just want ketones. I want you to maintain muscle and I want you to taste something incredibly mouthwatering. So I added in 18 grams of hydrolyzed collagen protein for muscle and joint support, healthy fats from nuts like cashew and cacao butter."
Hydrogen Water Discussion
Yeah, no, that's very cool. I mean, the other one I'm doing right now is just breathing in high, you know, aerosolized high.
"So essentially, hydrogen gas is almost like a hormetic stress that's inducing mitochondrial growth. You know, Mort Nicholson was kind of one of the big, you know, forerunners. If you look up Nicholson and his papers, he was one of the early researchers that I ended up writing with."
