Summary
Clinical pharmacist Jim LaValle joins Ben Greenfield to discuss innovative approaches to health, performance, and longevity. They cover peptides and small molecules for mitochondrial and kidney support, improving VO2 max, brain function, and sleep. LaValle explains his Metabolic Code test for identifying health bottlenecks.
The conversation explores peptides like KPV, BPC-157, and lorazotide for gut healing, and examines trends LaValle sees in high performers - including stress-driven hormone changes and subtle signs of inflammation. They discuss how personalized lab testing, wearable data, and smart supplementation can optimize performance and aging.
Key Points
- Peptides like KPV, BPC-157, and lorazotide can support gut healing
- The Metabolic Code test identifies major bottlenecks in health optimization
- Even high performers show stress-driven hormone changes and hidden inflammation
- Personalized lab testing combined with wearable data enables smarter supplementation
- Small molecules can support mitochondrial function and kidney health
- VO2 max improvement strategies discussed alongside brain function optimization
Key Moments
Vo2Max Training: How To
My son runs that company. There's a lot of different ways liposomes are made, man.
"My son runs that company. And I was looking for how to deliver small molecules or peptides in a solid state. And so I partnered with a pharmaceutical scientist and their liposomes. So everybody here's liposomes."
Thyroid Health Discussion
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Sodium Bicarbonate Discussion
You're probably a pre-diabetic and you haven't taken care of your insulin for a long time, then triad one. What the nephrologist does is gives you baking soda capsules.
"What the nephrologist does is gives you baking soda capsules."
Gut Microbiome: Probiotics
You're probably a pre-diabetic and you haven't taken care of your insulin for a long time, then triad one. What the nephrologist does is gives you baking soda capsules.
"They give you baking soda capsules so that you can suspend the time until you actually need to start dialysis. Because when you alkalineize the urine, well, your kidneys, it takes the pressure off the damage to them."
Collagen Discussion
Not only an energy bar, but the world's first ketone-powered energy bar.
"But I didn't just want ketones. I want you to maintain muscle and I want you to taste something incredibly mouthwatering."
Hydrogen Water Discussion
Yeah, no, that's very cool. I mean, the other one I'm doing right now is just breathing in high, you know, aerosolized high.
"So essentially, hydrogen gas is almost like a hormetic stress that's inducing mitochondrial growth. You know, Mort Nicholson was kind of one of the big, you know, forerunners."
