EWOT (Exercise With Oxygen Therapy)

Otto Warburg's Nobel Prize: oxygen deprivation creates cancer

Brad explains Warburg's Nobel Prize research showing that any cell can become cancerous when deprived of oxygen, and that cancer accelerates in low-oxygen environments. The 2019 Nobel Prize continued this research on cellular hypoxia response.

"you can take a regular cell and turn it into a cancer cell simply by starving it of oxygen. And he also found that when you put a cell or when you put cancer rather in a low oxygen environment, it accelerates its growth."

Cancer survival rate directly correlates with tumor oxygen status

Brad presents research showing that tumor oxygen levels directly predict patient outcomes. Higher oxygen means higher survival rates, and traditional therapies like chemotherapy perform better in oxygen-rich tumor environments.

"the lower the oxygen status of the tumor, the lower the survival rate. And transversely, the higher the oxygen status, even when you're taking traditional cancer therapies such as chemotherapy, radiation, or immunotherapy, they perform better in a high oxygen environment"

Von Ardenne's research showed durable capillary reopening from EWOT

Brad describes how the founder of EWOT demonstrated that even two or three sessions could create anti-inflammatory effects in endothelial cells, reestablishing blood flow that persisted weeks and months later.

"he was able to create this anti-inflammatory effect in those endothelial cells that re-established normal oxygenation downstream. And it was persistent, meaning people did it a few times and then they came back several weeks later and they still had this re-establishment of normal blood flow. And so"

T-cell and red blood cell counts improve dramatically with EWOT

Brad reports clinical observations where cancer patients using EWOT showed dramatic increases in T-cell and red blood cell counts, as flooding the body with oxygen enables the immune system to function at full capacity.

"we've actually seen some results from folks who are doing EWOT with cancer where their T cells and the red blood cells have gone up dramatically from doing EWOT"

EWOT benefits are most dramatic for people closer to the sickness end of the spectrum

Andy explains that EWOT impact scales with how far someone is on the sickness-to-wellness spectrum. People with more health challenges notice more dramatic improvements from supplemental oxygen during exercise.

"how far are you on this sickness to wellness? And what I'm realizing for just people that are doing it for overall general well being, like the closer they are to that sickness, the more of an impact that they're noticing on the EWOT."

Exercise with oxygen therapy for endurance performance gains

Phil introduces EWOT as a modality Andy has been using on his bike for endurance performance, wearing a mask hooked up to an oxygen reservoir during intense cycling sessions.

"something I've been seeing on Andy's Instagram quite often lately is him wearing this crazy mask hooked up to a bike and he's just going all out on the bike"

Oxygen as the gating factor for ATP production in exercise

The Critical Oxygen podcast frames EWOT within exercise physiology, focusing on how oxygen is the rate-limiting factor for mitochondrial ATP production during physical exertion.

"Welcome back to the Critical Oxygen Podcast, where we help you optimize your physiology and maximize your athletic potential"

How EWOT reopens inflamed capillaries and restores youthful blood flow

Brad explains von Ardenne's discovery that inflammation causes capillaries to swell shut, cutting off oxygen to downstream cells. EWOT creates an anti-inflammatory effect that reopens these capillaries and restores more youthful blood flow, even durably after just a few sessions.

"And now all the cells downstream are no longer getting oxygen. The red blood cells can't get through. And so the cells switch from aerobic respiration, which is making energy with oxygen to anaerobic respiration, which is making energy without it. And that creates a variety of problems in our body. Number one,"

EWOT vs hyperbaric: exercise pulls oxygen in instead of pressure pushing it

Brad compares EWOT to hyperbaric oxygen therapy, explaining that HBOT uses pressure to push oxygen through lungs while the body vasoconstricts to limit it. EWOT uses exercise to pull oxygen through dilated blood vessels with faster heart rate, creating deeper oxygenation.

"What you simply do is you do like 15 minutes of cardio while you have a mask on that you're breathing near pure oxygen. Because your body is so tuned in when you're exercising to bring in more oxygen, you're breathing deeper and heavier, your heart's beating faster, your blood vessels are dilating. All these physiological changes are your body's way of"

EWOT drives mitogenesis and maximizes fat burning

Brad explains how EWOT ramps up and maximizes mitochondria through mitogenesis, generating brand new mitochondria. This improves not just energy and alertness but also fat burning, memory, and cellular function throughout the body.

"And as I told you, low oxygenation causes inflammation. So it's a combination of not having enough energy and also fighting the inflammation. Once you start doing the oxygen, of course, that quickly can go away, which is amazing. Some of the first things folks tell me all the time is like, man, I did it the first time. And like my brain fog was, was gone for the rest of that day sort of thing. And they were kind of shocked by it. This is like brand new to me. I've"

No risk of oxygen toxicity during EWOT due to exercise-produced CO2

Brad addresses safety concerns, explaining that oxygen toxicity cannot occur during EWOT because exercise produces massive amounts of CO2 which creates pressure to drive oxygen out of blood vessels. The only real risks are fire safety and normal exercise injuries.

"uh there's about 21 oxygen in the air and it takes that and purifies it up to 93 which is a medical grade oxygen the challenge with the device is you know they can produce five or ten liters of oxygen in a minute and when you're exercising you can easily use 50 or 60 liters in a minute so they don't produce near enough oxygen so what we do is we take that device and we fill a large reservoir that's like a thousand liters so"

Otto Warburg's discovery that oxygen deprivation creates cancer cells

Brad explains Otto Warburg's Nobel Prize-winning research from the 1920s showing that normal cells can be turned cancerous simply by depriving them of oxygen, establishing the foundational link between hypoxia and cancer.

"he could turn any normal cell into a cancer cell simply by starving it of oxygen. And he also found that when you put a cell or when you put cancer rather in a low oxygen environment, it accelerates its growth."