Cognitive enhancement of healthy older adults using hyperbaric oxygen - a randomized controlled trial

Hadanny A, Daniel-Kotovsky M, Suzin G, et al. (2021) Aging
Title and abstract of Cognitive enhancement of healthy older adults using hyperbaric oxygen - a randomized controlled trial

Key Takeaway

HBOT improved cognitive function and increased cerebral blood flow in healthy adults over 64, suggesting oxygen therapy benefits brain aging.

Summary

This randomized controlled trial examined the effects of hyperbaric oxygen therapy on cognitive function in healthy aging adults.

Key findings:

  • 63 healthy adults aged 64+ completed the study
  • 60 HBOT sessions over 3 months
  • Significant improvements in attention, information processing, and executive function
  • Increased cerebral blood flow on imaging

Results:

  • Memory improvement: Significant gains in multiple domains
  • Processing speed: Enhanced information processing
  • Brain imaging: Increased blood flow to cognitive regions

Protocol:

  • 60 sessions, 5 days/week for 12 weeks
  • 100% oxygen at 2 ATA
  • 90 minutes per session

Clinical significance:

While this is HBOT (hyperbaric), it supports the concept that enhanced oxygen delivery benefits brain function, providing mechanistic support for EWOT approaches.

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Source

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DOI: 10.18632/aging.103571