Hyperbaric oxygen therapy - future prospects in regenerative therapy and anti-aging

Gupta N, Rathored J (2024) Frontiers in Aging
hyperbaric-oxygen-therapy hbot longevity regenerative-medicine review
Title and abstract of Hyperbaric oxygen therapy - future prospects in regenerative therapy and anti-aging

Key Takeaway

Comprehensive review of HBOT mechanisms for anti-aging, including effects on telomeres, senescence, stem cells, and neuroplasticity.

Summary

This 2024 review article comprehensively examines the mechanisms by which HBOT may promote regeneration and combat aging.

Key mechanisms reviewed:

  • Hyperoxia-hypoxia paradox and HIF-1α activation
  • Telomere lengthening effects
  • Senescent cell clearance
  • Stem cell mobilization
  • Angiogenesis and neurogenesis
  • Mitochondrial biogenesis

The authors conclude HBOT has enormous potential in regenerative and anti-aging therapy.

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