Key Takeaway
Meta-analysis found HBOT significantly improves neurocognitive deficits in TBI patients compared to baseline.
Summary
This 2025 systematic review and meta-analysis evaluated the effectiveness of HBOT for treating neurocognitive deficits following traumatic brain injury.
The analysis found significant improvements in cognitive function across multiple domains. However, the authors note that larger trials with standardized protocols are needed to establish optimal therapeutic use.
Current evidence suggests HBOT may be recommended for chronic TBI patients with prolonged post-concussion syndrome who show evidence of metabolic dysfunction on neuroimaging.