Key Takeaway
Double-blind RCT of 40 HBOT sessions for persistent brain injury symptoms showed encouraging results for post-injury sequelae.
Summary
This 2025 double-blind randomized trial compared 40 hyperbaric oxygen sessions to 40 sham sessions over 12 weeks in adults with persistent symptoms following non-stroke brain injury.
The study used 1.5 ATA, which has been studied extensively for brain injury sequelae. Prior trials of HBO2 show encouraging results for improvement of symptoms months to years after traumatic brain injury, stroke, and long COVID.
Figures
Figure 1