Dr. Jockers Functional Nutrition

The Science of Protein Cycling, Autophagy and Fat Loss with Vanessa Spina

Dr. Jockers Functional Nutrition with Vanessa Spina 2025-12-02

Summary

Vanessa Spina joins Dr. Jockers to discuss the science behind protein cycling for maximizing autophagy and fat loss. They explain how alternating between high and low protein days can optimize both mTOR-driven muscle building and AMPK-driven cellular cleanup.

Key Points

  • Protein cycling alternates high-protein and low-protein days for metabolic flexibility
  • Low-protein days enhance autophagy and cellular repair
  • High-protein days activate mTOR for muscle protein synthesis
  • This approach can break weight loss plateaus by varying metabolic signaling
  • Combining protein cycling with time-restricted eating amplifies benefits

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