Summary
Dr. David Jockers discusses the interplay between intermittent fasting, autophagy, and protein intake for controlling chronic inflammation. He explains how to balance protein consumption with fasting to maximize autophagy while maintaining muscle mass, and provides specific protocols for inflammation management.
Key Points
- Autophagy peaks during extended fasting periods of 18+ hours
- Protein cycling can enhance autophagy without sacrificing muscle
- mTOR activation from protein must be balanced with AMPK from fasting
- Specific amino acids like leucine have outsized effects on mTOR
- Anti-inflammatory benefits of fasting are dose-dependent on duration
