Summary
Dave Asprey's solo deep dive on modafinil covers 20 years of personal use, the neuroscience of how it activates wakefulness circuits, mitochondrial benefits, stacking protocols, and the real risks.
Key Points
- Aging can be slowed
- Multiple pathways to target
- Testing guides interventions
- Lifestyle is foundational
- Technology accelerating
- Personal optimization key
Key Moments
Cold exposure + modafinil stack: "neurochemical rocket fuel" for focus and energy
Asprey recommends stacking cold exposure with modafinil for an amplified neurochemical boost. He uses cryotherapy at his Upgrade Labs facilities and considers the combination one of the most potent biohacking stacks.
"Cold exposure with modafinil is like neurochemical rocket fuel."
