The Human Upgrade

Modafinil Masterclass: Clarity, Drive, and Longevity | Solo Pod : 1337

The Human Upgrade with Dave Asprey 2025-09-30

Summary

Dave Asprey discusses longevity science and practical anti-aging interventions.

Key Points

  • Aging can be slowed
  • Multiple pathways to target
  • Testing guides interventions
  • Lifestyle is foundational
  • Technology accelerating
  • Personal optimization key

Key Moments

Cold exposure + modafinil stack: "neurochemical rocket fuel" for focus and energy

Asprey recommends stacking cold exposure with modafinil for an amplified neurochemical boost. He uses cryotherapy at his Upgrade Labs facilities and considers the combination one of the most potent biohacking stacks.

"Cold exposure with modafinil is like neurochemical rocket fuel."

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