The Human Upgrade

These Plants Turn On 1,100 Healing Genes In 24 Hours (Ancient Biohacks) : 1346

The Human Upgrade with Dave Asprey 2025-10-16

Summary

The Human Upgrade episode covering biohacking strategies for peak performance and longevity.

Key Points

  • Biohacking for optimization
  • Technology and biology combined
  • Practical implementation

Key Moments

Neurogenesis

Your brain replaces all component parts every 22 days

Alberto Villoldo explains that while you cannot grow new neurons except in the hippocampus, every component part of existing neurons (mitochondria, organelles) is exchanged every 22 days. This means you need proper neuronutrients to build a healthy replacement brain.

"You grow a new brain every 22 days."

Lithium orotate as an essential neuronutrient from shamanic traditions

Villoldo connects Amazonian shamanic plant knowledge to modern neuroscience, highlighting NRF2 activation and detox pathways. He specifically recommends lithium orotate as something everybody should be taking now.

"They couldn't talk about NRF2 activation and detox processes and how you're missing lithium aortate that everybody should be taking now."

How parasites destroyed his brain and shamanic practices rebuilt it

Villoldo shares his personal story of contracting all five types of hepatitis, parasites in his brain, and a dead liver from years of anthropological fieldwork. He turned to the shamanic practices and neuronutrients he studied in the Amazon to regenerate his health.

"I had a dead liver, heart full of holes, and dead parasites in my brain."

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