Summary
Siim Land began researching human health at the age of 19 with a particular interest in longevity. What is the single most powerful thing that determines how long someone will live? What are the biomarkers to keep an eye on to prevent heart disease? How do you use a sauna to reduce all cause mortality? Is muscle mass or muscle strength associated with greater mortality reduction? He shares his thoughts on all of those topics and more including: why he likes the supplement GlyNAC, what gives him the best sleep, thoughts on why you don't want LDL cholesterol to get too high, C reactive protein, intermittent fasting, blue zones, eating seasonally, protein restriction, consuming fiber, rapamycin, deuterium, and why he isn't a fan of senolytic supplements. Siim's website: https://www.siimland.
Key Points
- Longevity-promoting strategies and interventions
- Deuterium depletion for mitochondrial function and longevity
- Practical health optimization strategies discussed
- Evidence and experience-based supplement recommendations
- Holistic approach to understanding chronic health issues
Key Moments
Intermittent fasting sparked a biohacking journey
Sim Land started intermittent fasting around 2013-2014 for body composition, which led him deeper into biohacking and longevity research.
"That's the time I started doing intermittent fasting because that was pretty popular back in 2013, 2014 era."
Sauna 4x/week cuts all-cause mortality by 40%
Finnish studies show sauna use four times per week reduces all-cause mortality by 40%, heart disease by 63%, and dementia risk by 66% versus once weekly.
"Doing the sauna four times a week reduces all-cause mortality by 40% and heart disease risk by 63% and Alzheimer's and dementia risk by 66%."
A 6-hour eating window with two meals per day
Sim Land eats in roughly a 6-hour window with a light protein snack at 11am and dinner around 5pm, stopping four hours before bed.
"I'll stop eating around four hours before bed. So I guess the eating window is like six hours, but there's only like two meals in between there."
