The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers

Bannai M, Kawai N, Ono K, Nakahara K, Murakami N (2012) Frontiers in Neurology
Title and abstract of The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers

Key Takeaway

3g glycine improved next-day cognitive performance and reduced fatigue in sleep-restricted subjects.

Summary

This study examined whether glycine could mitigate the effects of sleep restriction on next-day performance. Healthy volunteers had their sleep restricted to 5.5 hours, then received glycine or placebo.

Glycine significantly reduced fatigue and sleepiness, and improved psychomotor vigilance task performance the next day. The effects were attributed to improved sleep quality during the restricted sleep period.

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