Glycine ingestion improves subjective sleep quality in human volunteers, correlating with polysomnographic changes

Yamadera W, Inagawa K, Chiba S, Bannai M, Takahashi M, Nakayama K (2007) Sleep and Biological Rhythms
Title and abstract of Glycine ingestion improves subjective sleep quality in human volunteers, correlating with polysomnographic changes

Key Takeaway

3g glycine before bed improved subjective sleep quality and reduced daytime sleepiness in people with sleep complaints.

Summary

This placebo-controlled crossover study examined the effects of glycine on sleep quality in volunteers who had been continuously unsatisfied with their sleep. Participants received 3g glycine or placebo before bed.

Glycine significantly improved subjective sleep quality, sleep efficacy, and reduced daytime sleepiness. Polysomnographic analysis showed glycine shortened latency to sleep onset.

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DOI: 10.1111/j.1479-8425.2007.00262.x