A randomized controlled clinical trial of a Wim Hof Method intervention in women with high depressive symptoms.

Blades R, Mendes WB, Don BP, et al. (2024) Comprehensive psychoneuroendocrinology
Title and abstract of A randomized controlled clinical trial of a Wim Hof Method intervention in women with high depressive symptoms.

Key Takeaway

In women with high depressive symptoms, the Wim Hof Method reduced rumination compared to slow breathing with warm showers, suggesting stress recovery benefits similar to exercise

Summary

This RCT randomized 84 healthy midlife women with high stress and depressive symptoms to either WHM (breathing technique + cold showers) or active comparison (slow-paced breathing + warm showers) for three weeks. The only significant between-group difference was reduced daily rumination in the WHM group during the first two weeks.

Methods

Randomized controlled trial with 84 midlife women with high stress and depressive symptoms. WHM group (n=41): breathing technique for intermittent hypoxia + cold showers. Control group (n=43): slow-paced breathing + warm showers. Daily audio instructions (15 min) for 3 weeks. Primary outcomes: depressive symptoms, anxiety, perceived stress.

Key Results

Both groups showed improvements in depressive symptoms, anxiety, and stress. Significant between-group difference only for daily rumination - WHM group reported reduced rumination in first two weeks. Suggests WHM may reduce depression through stress recovery mechanisms similar to exercise.

Figures

Limitations

Active comparator makes it difficult to isolate WHM-specific effects. Self-reported outcomes. Only women included. Short 3-week intervention. Rumination was not a primary outcome. Both groups improved, limiting ability to detect between-group differences.

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Source

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DOI: 10.1016/j.cpnec.2024.100272