Fasting and cancer: molecular mechanisms and clinical application

Nencioni A, Caffa I, Cortellino S, Longo VD (2019) Nature Reviews Cancer
Title and abstract of Fasting and cancer: molecular mechanisms and clinical application

Key Takeaway

Short-term fasting triggers immune system regeneration and may enhance resistance to infection while reducing inflammation.

Summary

This review examines how short-term fasting affects immune function.

Periodic fasting can trigger autophagy, stem cell regeneration, and immune system recalibration, potentially enhancing infection resistance and reducing chronic inflammation.

Methods

  • Literature review
  • Multiple fasting protocols
  • Immune outcome analysis
  • Mechanism discussion

Key Results

  • Triggers autophagy
  • Promotes stem cell activity
  • Reduces inflammation
  • May enhance immunity

Figures

Limitations

  • Varied fasting protocols
  • Individual responses differ
  • Not suitable for all

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Source

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DOI: 10.1038/s41568-018-0061-0