Key Takeaway
Eight sessions of carboxytherapy improved stretch marks with objective 3D imaging showing better skin topography and histology confirming collagen remodeling.
Summary
This clinical trial evaluated carboxytherapy for stretch marks (striae distensae) in 20 patients using both objective measurements and histological analysis.
Patients received 8 sessions of CO2 injection at 2-week intervals. Computerized 3D camera imaging objectively assessed skin topography changes, and skin biopsies confirmed histological improvements.
Methods
- 20 patients with striae distensae
- 8 sessions at 2-week intervals
- Carboxy-gun delivery system
- Computerized 3D camera for objective skin topography analysis
- Skin biopsies before and 4 months after treatment
- Photography documentation
Key Results
- Significant clinical improvement in striae
- 3D imaging confirmed improved skin topography
- Histology showed:
- Increased collagen deposition
- More compact and organized collagen fibers
- Increased elastic fibers in normal pattern
- Minimal side effects and low downtime
- Results maintained at 4-month follow-up
Limitations
- Small sample size (n=20)
- No control group
- 4-month follow-up (longer-term durability unknown)
- Single treatment protocol