The Human Upgrade

Biohacking News Weekly Update : 1383

The Human Upgrade with Dave Asprey 2025-12-19

Summary

Dave Asprey joins The Human Upgrade to discuss biohacking news weekly update : 1383. Key topics include practical biohacking tools and technologies for health optimization; performance optimization strategies backed by science; key longevity markers and interventions to optimize healthspan.

Key Points

  • Practical biohacking tools and technologies for health optimization
  • Performance optimization strategies backed by science
  • Key longevity markers and interventions to optimize healthspan

Key Moments

Creatine

Most people take creatine the wrong way and miss brain benefits

Dave Asprey explains that standard creatine supplements miss the critical conversion step to phosphocreatine, the form cells actually use for energy during exercise and mental work, and that magnesium is the required co-factor for this conversion.

"Your cells need phosphocratine for immediate energy during exercise and mental work, and your body has to convert normal creatine into phosphocratine in order to use it."

Seed oils account for 20 percent of average daily calories

Asprey highlights that seed oils make up roughly 20 percent of the average person's daily caloric intake and that recent studies link them to metabolic issues and inflammation.

"even if you think it's healthy, it probably contains seed oils, which make up 20% of the average person's daily calories. And recent studies show seed oils can cause metabolic issues and inflammation in your body."

Nixtamalization removes mycotoxins from corn products

Asprey explains that nixtamalization is a traditional process that removes mycotoxins and anti-nutrients from corn, making it one of the rare cases where he will eat corn-based products.

"This is one of the few times I'll eat corn because this corn is nixtamilized, which is a process that removes mycotoxins and anti-nutrients."

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