The Human Upgrade

Jet Lag Superdrug, 25% Dementia Drop, Coffee Brain Aging, Kratom Shakeup : 1415

The Human Upgrade with Dave Asprey 2026-02-13

Summary

Dave Asprey joins The Human Upgrade to discuss jet lag superdrug, 25% dementia drop, coffee brain aging, kratom shakeup : 1415. Key topics include protocols for cognitive enhancement and neuroprotection; key longevity markers and interventions to optimize healthspan; practical takeaways for implementing discussed protocols.

Key Points

  • Protocols for cognitive enhancement and neuroprotection
  • Key longevity markers and interventions to optimize healthspan
  • Practical takeaways for implementing discussed protocols
  • Key research findings and their real-world applications
  • Expert insights on optimizing health outcomes

Key Moments

Caffeine

Jet lag superdrug and cognitive enhancement protocols

Dave Asprey discusses a potential jet lag superdrug alongside protocols for cognitive enhancement and neuroprotection, connecting circadian rhythm disruption to accelerated brain aging.

"Protocols for cognitive enhancement and neuroprotection"
Caffeine

Coffee and brain aging research findings

The episode covers new research on coffee's impact on brain aging, the surprising finding that dementia risk dropped 25 percent in a new study, and how caffeine interacts with cognitive function over time.

"Key longevity markers and interventions to optimize healthspan"
Caffeine

Kratom regulatory changes and practical implications

Asprey covers the latest kratom regulatory shakeup and its implications for biohackers, alongside practical takeaways for implementing cognitive enhancement protocols discussed in the episode.

"Practical takeaways for implementing discussed protocols"

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