The Human Upgrade

What If You Stop Eating For 72 Hours? : 1375

The Human Upgrade with Dave Asprey 2025-12-07

Summary

Dave Asprey joins The Human Upgrade to discuss what if you stop eating for 72 hours? : 1375. Key topics include nutritional strategies based on current research; performance optimization strategies backed by science; practical biohacking tools and technologies for health optimization.

Key Points

  • Nutritional strategies based on current research
  • Performance optimization strategies backed by science
  • Practical biohacking tools and technologies for health optimization
  • Key longevity markers and interventions to optimize healthspan

Key Moments

What happens to your body during a 72-hour fast

Dave Asprey explores the physiological changes that occur during a 72-hour fast, from initial glycogen depletion through deep ketosis and autophagy activation, explaining the benefits and risks at each stage.

"Every time you reach for a healthy snack, you could be sabotaging your energy, f"

Practical biohacking tools to make extended fasting easier

The episode covers practical biohacking tools and supplements that make extended fasting more manageable, including electrolyte strategies and specific compounds that support the body during prolonged food restriction.

"Every time you reach for a healthy snack, you could be sabotaging your energy, f"

Longevity benefits of periodic 72-hour fasting protocols

Asprey discusses the longevity markers that improve with periodic extended fasting, including stem cell regeneration, immune system reset, and improved insulin sensitivity, drawing on both research and his personal experience.

"Every time you reach for a healthy snack, you could be sabotaging your energy, f"

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