ZOE Science & Nutrition

Recap: Is it time for you to try fasting? | Dr Valter Longo & Tim Spector

ZOE Science & Nutrition with Jonathan Wolf 2025-12-09

Summary

Jonathan Wolf covers is it time for you to try fasting? | dr valter longo & tim spector. Key topics include protocols and timing strategies for fasting interventions; nutritional strategies based on current research; practical takeaways for implementing discussed protocols.

Key Points

  • Protocols and timing strategies for fasting interventions
  • Nutritional strategies based on current research
  • Practical takeaways for implementing discussed protocols
  • Key research findings and their real-world applications
  • Expert insights on optimizing health outcomes

Key Moments

Time Restricted Eating: So if you're not willing to fast yourself for

So if you're not willing to fast yourself for five days, is there any positive impact on your body from fasting more rapidly because you're talking about how it's, it transforms your body in five days, most people listening are probably not going to fast for five days, but obviously there's a lot of

"So if you're not willing to fast yourself for five days, is there any positive impact on your body from fasting more rapidly because you're talking about how it's, it transforms your body in five days, most people listening are probably not going to fast for five days, but obviously there's a lot of interest in intermittent fasting or all these other sort of things, is there any impact on your body from shorter periods of fasting? Yeah,"

And so I think that's a good safe option to the 16 hours

And I think fasting, because it is so powerful, is in the same category, but the 12 hours I've never seen any negative studies, epidemiological or otherwise.

"And I think fasting, because it is so powerful, is in the same category, but the 12 hours I've never seen any negative studies, epidemiological or otherwise. So I would say that that's a very good recommendation, it seems to be working for aging, it seems to be working for metabolic issues, not as well as the 16 hours, but well. And so I think that's a good safe option to the 16 hours."

So they get closer to the 12

You told them to go 10 hours, but did it because in the studies of Sachin Panda, he tells them 10 hours, but then it's about 11, right? Yes, we did and a third did it quite sort of religiously and there was this middle group that actually went back and probably managed 12 hours most of the time, but

"You told them to go 10 hours, but did it because in the studies of Sachin Panda, he tells them 10 hours, but then it's about 11, right? So they get closer to the 12. So do you know what they actually was that they did? Yes, we did and a third did it quite sort of religiously and there was this middle group that actually went back and probably managed 12 hours most of the time, but they didn't seem to get quite the same benefits."

By the end of it, they saw five days per month

We ask, and the University of Lydin trial with 100 patients actually looked at lifestyle, and saw no difference other than a little bit increasing exercise towards the end of the 12 fast did mimicking diet cycle.

"We ask, and the University of Lydin trial with 100 patients actually looked at lifestyle, and saw no difference other than a little bit increasing exercise towards the end of the 12 fast did mimicking diet cycle. So they did monthly, so these diabetics with doing fast did mimicking that once a month for 12 months. By the end of it, they saw five days per month. Five days per month."

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