Shockwave Therapy (ESWT) Research

6 peer-reviewed studies supporting this intervention. Evidence rating: A

6 Studies
0 RCTs
2 Meta-analyses
2020-2024 Year Range

Study Comparison

Study Year Type Journal Key Finding
Cp A et al. 2024 Study Scientific reports Adding ESWT to conventional physical therapy significantly improved functional disability even in severe (grade IV) knee osteoarthritis.
Perveen W et al. 2024 Study Scientific reports ESWT significantly outperformed ultrasound therapy for pain reduction at 1, 3, and 6 months, and grip strength improvement at 3 months in tennis elbow patients.
Xiong Y et al. 2024 Study Frontiers in medicine Systematic review confirms ESWT is effective and safe for treating upper limb tendinopathies including rotator cuff, lateral epicondylitis, and biceps tendonitis.
Elgendy MH et al. 2024 Meta-analysis Physiotherapy research international : the journal for researchers and clinicians in physical therapy ESWT significantly reduces pain and improves function in both calcific and non-calcific tendinopathies of the upper and lower limbs compared to placebo.
Xue X et al. 2024 Systematic review BMC musculoskeletal disorders ESWT significantly improves pain, shoulder function, and range of motion in rotator cuff tendinopathy, with benefits seen across multiple validated outcome measures.
Zhang Q et al. 2020 Systematic review and meta-analysis Archives of physical medicine and rehabilitation ESWT significantly reduces pain intensity and improves functional outcomes in myofascial pain syndrome of the trapezius compared to sham or conventional treatments.

Study Details

Cp A, Jayaraman K, Babkair RA, Nuhmani S, Nawed A, Khan M, Alghadir AH

Scientific reports

Key Finding: Adding ESWT to conventional physical therapy significantly improved functional disability even in severe (grade IV) knee osteoarthritis.
View Summary

This randomized controlled trial examined whether adding extracorporeal shockwave therapy (ESWT) to conventional physical therapy improves outcomes in patients with severe knee osteoarthritis.

Results showed significant functional improvements in the ESWT group compared to physical therapy alone, demonstrating that ESWT can benefit even advanced osteoarthritis cases.

Perveen W, Anwar S, Hashmi R, Ali MA, Raza A, Ilyas U, Nuhmani S, Khan M, Alghadir AH

Scientific reports

Key Finding: ESWT significantly outperformed ultrasound therapy for pain reduction at 1, 3, and 6 months, and grip strength improvement at 3 months in tennis elbow patients.
View Summary

This randomized controlled trial compared extracorporeal shockwave therapy (ESWT), ultrasound therapy, and deep friction massage for treating lateral epicondylitis (tennis elbow).

ESWT demonstrated superior outcomes for both pain reduction and functional improvement compared to ultrasound, with benefits persisting through 6-month follow-up.

Xiong Y, Wen T, Jin S, Lin L, Shao Q, Peng Y, Zheng Q, Li W

Frontiers in medicine

Key Finding: Systematic review confirms ESWT is effective and safe for treating upper limb tendinopathies including rotator cuff, lateral epicondylitis, and biceps tendonitis.
View Summary

This systematic review and meta-analysis examined the efficacy and safety of extracorporeal shockwave therapy for various upper limb tendon conditions.

Analysis of multiple randomized controlled trials found consistent evidence supporting ESWT effectiveness for rotator cuff tendinopathy, lateral epicondylitis, and biceps tendonitis, with a favorable safety profile.

Elgendy MH, Khalil SE, ElMeligie MM, et al.

Physiotherapy research international : the journal for researchers and clinicians in physical therapy

Key Finding: ESWT significantly reduces pain and improves function in both calcific and non-calcific tendinopathies of the upper and lower limbs compared to placebo.
View Summary

This systematic review and meta-analysis evaluated the effectiveness of extracorporeal shockwave therapy (ESWT) for treating tendinopathies across both upper and lower extremities. The review synthesized evidence from randomized controlled trials comparing ESWT to placebo or sham treatments for conditions including lateral epicondylitis, rotator cuff tendinopathy, patellar tendinopathy, Achilles tendinopathy, and plantar fasciitis.

The pooled results demonstrated that ESWT produced statistically significant improvements in both pain reduction and functional outcomes across multiple tendinopathy types. The analysis examined both calcific and non-calcific tendinopathies, finding benefits in both categories. The findings support ESWT as an effective non-invasive treatment option for chronic tendon disorders that have not responded to conventional conservative management.

The review strengthens the evidence base for ESWT as a versatile intervention applicable across different anatomical sites and tendinopathy types, suggesting it should be considered as part of the treatment algorithm for persistent tendon pain in both upper and lower limbs.

Xue X, Song Q, Yang X, et al.

BMC musculoskeletal disorders

Key Finding: ESWT significantly improves pain, shoulder function, and range of motion in rotator cuff tendinopathy, with benefits seen across multiple validated outcome measures.
View Summary

This systematic review and meta-analysis examined the effectiveness of extracorporeal shockwave therapy (ESWT) specifically for rotator cuff tendinopathy, one of the most common causes of shoulder pain. Published in BMC Musculoskeletal Disorders, the review pooled data from randomized controlled trials evaluating ESWT against control treatments for rotator cuff conditions.

The analysis assessed multiple validated outcome measures including Visual Analog Scale (VAS) for pain, Constant-Murley Score (CMS), UCLA Shoulder Score, range of motion (ROM), American Shoulder and Elbow Surgeons (ASES) score, and total effective rate (TER). Across these measures, ESWT consistently demonstrated significant improvements in pain relief, shoulder function, and mobility compared to control groups.

The comprehensive evaluation across six different outcome domains provides robust evidence supporting ESWT as an effective treatment for rotator cuff tendinopathy. The findings suggest ESWT can meaningfully improve both the pain experience and functional capacity in patients with this common shoulder condition, offering a non-invasive alternative to corticosteroid injections or surgery.

Zhang Q, Fu C, Huang L, et al.

Archives of physical medicine and rehabilitation

Key Finding: ESWT significantly reduces pain intensity and improves functional outcomes in myofascial pain syndrome of the trapezius compared to sham or conventional treatments.
View Summary

This systematic review and meta-analysis evaluated the efficacy of extracorporeal shockwave therapy (ESWT) for myofascial pain syndrome (MPS) specifically affecting the trapezius muscle. Published in Archives of Physical Medicine and Rehabilitation, the study addressed a common pain condition characterized by trigger points, referred pain patterns, and restricted range of motion in the neck and shoulder region.

The review synthesized data from randomized controlled trials comparing ESWT to sham treatment or conventional therapies for trapezius MPS. Primary outcomes included pain intensity measured via VAS or numeric rating scales and functional outcomes including range of motion and disability measures. The pooled analysis demonstrated that ESWT produced significant improvements in both pain and function compared to control groups.

The findings are clinically relevant because trapezius myofascial pain is extremely prevalent, particularly among office workers and those with repetitive strain. ESWT's ability to target trigger points and reduce pain offers a valuable treatment option beyond manual trigger point therapy, dry needling, or medication. The results support incorporating ESWT into the management of chronic trapezius MPS, especially for patients who have not responded to first-line conservative treatments.

Evidence Assessment

A Strong Evidence

This intervention is supported by multiple high-quality randomized controlled trials and/or meta-analyses showing consistent positive effects.