Key Takeaway
Medical ozone therapy induces controlled oxidative stress that upregulates antioxidant enzymes and may improve circulation and healing.
Summary
This scientific review presents the biochemical rationale for medical ozone therapy.
Low-dose ozone triggers adaptive responses including upregulation of antioxidant enzymes, improved oxygen delivery to tissues, and modulation of inflammatory processes.
Methods
- Biochemical mechanism review
- Clinical evidence synthesis
- Dose-response analysis
- Safety profile assessment
Key Results
- Upregulates Nrf2 pathway
- Increases antioxidant enzymes
- Improves tissue oxygenation
- Anti-inflammatory effects
Limitations
- Dose-dependent effects
- Delivery method matters
- Need more RCTs