Summary
Dr. Mark Hyman interviews Dr. Paolo Tordiglione, an Italian intensive care physician with an MD and PhD in ozone's effects on the brain, who has been treating COVID-19 patients with ozone therapy at a hospital in Rome. Dr. Tordiglione brings 20 years of clinical experience with ozone and serves as president of Doctors of the World for Italy and vice president of the Academy of Bioregenerative Medicine. The conversation provides a frontline medical perspective on ozone therapy during the pandemic. Dr. Tordiglione reports that COVID patients treated with ozone experienced no significant side effects, had better quality of life during their hospital stay, and none of his ozone-treated patients required ICU admission. He emphasizes that the virus behaves differently depending on the patient's baseline health and metabolic balance, and that ozone therapy works by enhancing the body's own immune and healing responses rather than as a direct antiviral agent. The episode highlights the contrast between European and American approaches to ozone therapy. While ozone is used in hospital settings in Italy and other European countries, it remains largely unavailable in the United States. Dr. Hyman frames the discussion as an opportunity to learn from international practices that could benefit American patients, noting the overwhelming scale of the pandemic at the time of recording with 55 million global cases and 1.3 million deaths.
Key Points
- Dr. Tordiglione has 20 years of experience using ozone therapy clinically and holds a PhD in ozone's effects on the brain
- None of his ozone-treated COVID patients required ICU admission, and they reported better quality of life during hospitalization
- Ozone-treated patients experienced virtually no side effects compared to standard treatment
- COVID outcomes depend heavily on the patient's metabolic balance and baseline health when infected
- Ozone therapy is used in hospital settings in Italy and other European countries but remains largely unavailable in the US
- Ozone works by enhancing the body's own immune response and healing mechanisms rather than as a direct antiviral
- The episode was recorded during a major COVID surge with 55 million global cases and 1.3 million deaths
Key Moments
Italian ICU physician's 20 years of ozone therapy experience
Dr. Paolo Tordiglione, an intensive care physician in Rome, describes his 20 years of experience working with ozone therapy and how COVID-19 continues to behave unpredictably across patients.
"I'd like to take a step back and talking about the ozone treatment that goes all the way back to 2000. I mean, so it's about 20 years that I do work with this molecule, with this extraordinary gas."
Ozone-treated COVID patients avoided ICU admission
Dr. Tordiglione reports that COVID patients treated with ozone had no side effects, better quality of life during infection, and none required ICU admission.
"The patients we treat with ozone did really have no side effects, did have a better life quality during the stay, during the infection. And we had none of the ones that we treated that went in the ICU."
Heparin and ozone combination for COVID treatment
Dr. Tordiglione explains the use of low molecular weight heparin alongside ozone therapy as part of the Italian hospital protocol, noting that this combination helped prevent rapid deterioration in COVID patients.
"The other thing that we use we've seen that improves a lot the outcome is using heparin low dose heparin low molecular weight heparin And we use 4,000 units twice a day."
