Key Takeaway
Review of ozone therapy mechanisms showing potential benefits through oxidative preconditioning, immune modulation, and improved oxygen delivery, though clinical evidence remains limited.
Summary
Comprehensive review of ozone therapy pharmacology and clinical applications.
Methods
- Narrative review
- Mechanisms of action
- Clinical applications
- Safety assessment
Key Results
- Oxidative stress preconditioning mechanism
- Immune system modulation
- Antimicrobial effects documented
- Various administration routes
- Safety profile acceptable with proper protocols
Limitations
- Limited high-quality RCTs
- Regulatory concerns
- Mechanism not fully understood
- Standardization lacking