Effect of Apple Cider Vinegar Intake on Body Composition in Humans with Type 2 Diabetes and/or Overweight: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Castagna A, Ferro Y, Noto FR, et al. (2025) Nutrients
Title and abstract of Effect of Apple Cider Vinegar Intake on Body Composition in Humans with Type 2 Diabetes and/or Overweight: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Key Takeaway

ACV supplementation significantly reduced body weight, BMI, and waist circumference in individuals with type 2 diabetes or overweight/obesity.

Summary

This systematic review and meta-analysis examined randomized controlled trials investigating the effect of apple cider vinegar (ACV) intake on body composition parameters in people with type 2 diabetes and/or overweight/obesity.

The pooled analysis demonstrated that ACV supplementation led to statistically significant reductions in body weight, body mass index (BMI), and waist circumference compared to placebo. The effects were consistent across studies, though the magnitude of weight loss was modest.

The authors highlighted that ACV may support weight management as a complementary approach alongside dietary and lifestyle modifications. However, they noted heterogeneity in study designs, dosages, and intervention durations, and called for larger, well-designed RCTs to establish standardized dosing recommendations and long-term efficacy.

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DOI: 10.3390/nu17183000