The Effects of Apple Cider Vinegar on Cardiometabolic Risk Factors: A Systematic Review and Meta-analysis of Clinical Trials.

Tehrani SD, Keshani M, Rouhani MH, et al. (2025) Current medicinal chemistry
Title and abstract of The Effects of Apple Cider Vinegar on Cardiometabolic Risk Factors: A Systematic Review and Meta-analysis of Clinical Trials.

Key Takeaway

Apple cider vinegar significantly reduced fasting blood glucose, HbA1c, total cholesterol, and triglycerides in a meta-analysis of clinical trials.

Summary

This systematic review and meta-analysis pooled data from clinical trials to evaluate the effects of apple cider vinegar (ACV) supplementation on cardiometabolic risk factors including blood glucose, lipid profiles, and body weight.

The analysis found that ACV intake led to statistically significant reductions in fasting blood glucose, HbA1c (a marker of long-term blood sugar control), total cholesterol, and triglycerides. These findings suggest ACV may have meaningful benefits for metabolic health, particularly in populations at risk of type 2 diabetes and cardiovascular disease.

The authors noted that while results were promising, the included trials varied in dosage, duration, and population characteristics. They recommended larger, longer-duration RCTs to confirm optimal dosing protocols and to determine whether these cardiometabolic improvements translate into reduced clinical events over time.

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Source

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DOI: 10.2174/0929867331666230822102021