Cyclic sighing in the clinic waiting room may decrease pain: results from a pilot randomized controlled trial.

Hanley AW, Davis A, Worts P, et al. (2025) Journal of behavioral medicine
Title and abstract of Cyclic sighing in the clinic waiting room may decrease pain: results from a pilot randomized controlled trial.

Key Takeaway

A 4-minute cyclic sighing exercise significantly reduced both pain unpleasantness and pain intensity in orthopedic clinic patients compared to a control condition.

Summary

This pilot randomized controlled trial investigated whether a brief cyclic sighing intervention could reduce acute clinical pain in patients waiting for x-rays at a walk-in orthopedic clinic. Participants were randomized to either a 4-minute asynchronous cyclic sighing exercise or a time- and attention-matched injury management control condition.

The study found that participants who performed cyclic sighing reported significantly less pain unpleasantness and pain intensity while waiting for their x-ray compared to controls. However, anxiety and depression symptoms did not differ significantly between groups.

These results suggest that brief, asynchronous breathwork interventions like cyclic sighing could be a practical, low-cost tool for managing acute pain in clinical settings. The asynchronous format — requiring no therapist or facilitator — makes it particularly scalable for integration into clinic waiting rooms.

Methods

Single-site pilot RCT conducted in the x-ray waiting room of a walk-in orthopedic clinic. Participants were randomized to a 4-minute asynchronous cyclic sighing intervention or a time- and attention-matched injury management control condition. Outcomes measured included pain unpleasantness, pain intensity, anxiety symptoms, and depression symptoms. The study was registered as NCT06292793.

Key Results

  • Cyclic sighing group reported significantly lower pain unpleasantness vs. controls
  • Cyclic sighing group reported significantly lower pain intensity vs. controls
  • No significant between-group differences in anxiety or depression symptoms
  • Effects observed after just 4 minutes of practice

Limitations

  • Pilot study with relatively small sample size
  • Single-site design limits generalizability
  • Short-term assessment only (immediate post-intervention)
  • Self-reported outcome measures
  • Orthopedic pain population may not generalize to other pain types
  • No long-term follow-up to assess durability of effects

Related Interventions

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Source

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DOI: 10.1007/s10865-024-00548-5