Clinical Effects of Hydrogen Administration: From Animal and Human Diseases to Exercise Medicine

Nicolson GL, Ferreira de Mattos G, Settineri R, Costa C, Ellithorpe R, Rosenblatt S, La Valle J, Jimenez A, Ohta S (2016) International Journal of Clinical Medicine
Title and abstract of Clinical Effects of Hydrogen Administration: From Animal and Human Diseases to Exercise Medicine

Key Takeaway

Systematic review of clinical trials found molecular hydrogen shows promise for oxidative stress-related conditions, though more rigorous trials are needed.

Summary

Comprehensive review of clinical trials examining molecular hydrogen (H2) therapy across various conditions.

Methods

  • Systematic review of clinical trials
  • Various H2 delivery methods
  • Multiple disease conditions
  • Safety and efficacy assessment

Key Results

  • Generally safe and well-tolerated
  • Antioxidant and anti-inflammatory effects
  • Promising for metabolic syndrome
  • Potential exercise recovery benefits
  • Variable study quality

Limitations

  • Many small studies
  • Heterogeneous protocols
  • Placebo control challenges
  • Mechanisms not fully understood

Related Interventions

Related Studies

Source

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DOI: 10.4236/ijcm.2016.71005