Use of Continuous Glucose Monitoring in Non-diabetic Individuals for Cardiovascular Prevention: A Systematic Review of Its Impact on Guiding Lifestyle Interventions.

Ahmed N, Elzein Ali MF, Hamed Mohamed MN, et al. (2025) Cureus
cgm
Title and abstract of Use of Continuous Glucose Monitoring in Non-diabetic Individuals for Cardiovascular Prevention: A Systematic Review of Its Impact on Guiding Lifestyle Interventions.

Key Takeaway

CGM use in non-diabetic individuals supports cardiovascular prevention by guiding dietary and exercise changes that reduce glucose variability and postprandial spikes.

Summary

This systematic review examined the evidence on continuous glucose monitoring (CGM) use in people without diabetes for cardiovascular risk prevention. The authors searched multiple databases and included studies that assessed CGM-guided lifestyle interventions in normoglycemic or prediabetic populations, focusing on outcomes related to cardiovascular health markers.

The review found that CGM provided actionable real-time feedback that helped participants make meaningful dietary and exercise modifications. Individuals using CGM were able to identify foods and meal patterns that triggered excessive postprandial glucose spikes, and adjust their habits accordingly. These behavioral changes led to measurable reductions in glycemic variability, a metric increasingly linked to endothelial dysfunction and early atherosclerosis risk.

The authors concluded that CGM shows promise as a preventive cardiology tool in non-diabetic populations, enabling personalized lifestyle interventions that target glucose dysregulation before it progresses to overt metabolic disease. However, they noted that more long-term randomized trials are needed to confirm whether CGM-guided changes translate into reduced cardiovascular events.

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Source

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DOI: 10.7759/cureus.94460