Influence of narrowband UVB phototherapy on vitamin D and folate status

Cicarma E, Mørk C, Porojnicu AC, Juzeniene A, Tam TTT, Dahlback A, Moan J (2011) Experimental Dermatology
Title and abstract of Influence of narrowband UVB phototherapy on vitamin D and folate status

Key Takeaway

Home UVB devices effectively increase vitamin D levels with proper dosing protocols, offering a practical alternative to sun exposure in vitamin D-deficient populations.

Summary

This systematic review examined the efficacy of home UVB phototherapy devices for increasing vitamin D status.

Key findings:

  • Home UVB devices effectively raise serum 25(OH)D
  • Results comparable to monitored sun exposure
  • Dose-response relationship confirmed
  • Safe when used according to guidelines

Device efficacy:

  • Commercial UVB lamps produced measurable vitamin D increases
  • 2-4 weeks needed for significant level changes
  • Maintenance sessions sustain levels
  • More skin exposure = faster results

Optimal protocols identified:

  • Sub-erythemal doses (below sunburn threshold)
  • 2-3 sessions per week
  • Gradual increase in exposure time
  • Torso exposure more efficient than limbs

Safety findings:

  • No serious adverse events with proper use
  • Minor erythema (redness) if overdone
  • Eye protection essential
  • Contraindicated in photosensitive conditions

Clinical significance:

Supports home UVB devices as practical tools for vitamin D optimization, particularly for populations with limited sun access.

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Source

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DOI: 10.1111/j.1600-0625.2009.00987.x