Key Takeaway
Landmark review establishing vitamin D deficiency as a global health issue, with sunlight exposure being the primary natural source of vitamin D synthesis.
Summary
Definitive review on vitamin D deficiency, its causes, consequences, and treatment.
Methods
- Comprehensive review
- Epidemiology of deficiency
- Health consequences
- Treatment approaches
Key Results
- Deficiency extremely common globally
- Sunlight primary natural source
- UVB exposure synthesizes vitamin D in skin
- Multiple health consequences of deficiency
- Supplementation effective when sun limited
Limitations
- Optimal levels debated
- Individual synthesis varies
- Skin type affects production
- Sun exposure risks exist