Association of daily step count and intensity with incident dementia

del Pozo Cruz B, Ahmadi M, Naiber SM, Stamatakis E (2022) JAMA Neurology
Title and abstract of Association of daily step count and intensity with incident dementia

Key Takeaway

Walking ~10,000 steps daily was associated with 51% lower dementia risk, with benefits starting at just 3,800 steps per day.

Summary

This large prospective study analyzed accelerometer data from 78,430 UK Biobank participants to examine the relationship between daily steps and dementia incidence.

Results showed a dose-response relationship, with optimal benefits around 9,800 steps daily. Even modest increases in daily steps were associated with meaningful reductions in dementia risk.

Methods

  • Prospective cohort study
  • 78,430 participants
  • 7-year follow-up
  • Accelerometer-measured steps

Key Results

  • 51% lower dementia risk at ~10,000 steps
  • Benefits begin at 3,800 steps/day
  • Dose-response relationship observed
  • Step intensity also matters

Figures

Limitations

  • Observational design
  • Single measurement period
  • Predominantly white UK population

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Source

View on PubMed →

DOI: 10.1001/jamaneurol.2022.2672