Key Takeaway
Meta-analysis of 12 RCTs found progressive muscle relaxation significantly reduces anxiety, pain, and improves quality of life in cancer patients
Summary
This systematic review and meta-analysis of 12 RCTs (1,147 cancer patients) examined PMR effects on health-related outcomes. Using Cochrane Risk of Bias 2.0 and GRADE, the study found significant effects on anxiety reduction (SMD = -1.32), pain relief (SMD = -1.02), and quality of life improvement (SMD = 1.65).
Methods
Systematic review and meta-analysis. Nine databases searched. Risk of bias assessed using Cochrane Risk of Bias 2.0. Evidence quality graded using GRADE. Meta-analysis performed using RevMan 5.4. Included 12 RCTs with 1,147 cancer patients.
Key Results
Significant anxiety reduction (SMD = -1.32, 95% CI: -1.88 to -0.75, P < 0.001). Significant pain reduction (SMD = -1.02). Quality of life improvement (SMD = 1.65). Large effect sizes across all outcomes.
Limitations
Heterogeneous cancer types and stages. Variable PMR protocols. Most studies from single countries. GRADE certainty varied. Some studies had high risk of bias. Short follow-up periods in most trials.