NAD+
NAD+ precursors, NMN, NR, and cellular energy
Studies
Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women
First rigorous human RCT showing NMN (250mg/day for 10 weeks) increased muscle insulin sensitivity by ~25% in prediabetic postmenopausal women.
Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
NR supplementation (500mg twice daily) was well-tolerated in older adults, increased NAD+ by ~60%, and showed trends toward reduced blood pressure and arterial stiffness.
Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men
250mg NMN daily for 12 weeks improved gait speed, grip strength, and NAD+ levels in healthy older men, suggesting functional benefits for aging muscle.
Podcast Episodes
#109 How To Boost NAD Levels To Fight Inflammation, Improve Recovery, and Slow Aging | Dr. Charles Brenner
with Dr. Charles Brenner
The Coolest, Craziest Oral Peptides (& Where To Get Them), Boosting Testosterone Without Drugs & More With LIFE Network Expert Kyal Van Der Leest
with Kyal Van Der Leest
The Superbrain Drug Politicians Use To Outsmart Everyone : 1399
with David Renteln
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver
with Dr. Craig Koniver
Supplements for Longevity & Their Efficacy | Dr. Peter Attia
with Dr. Peter Attia
Enjoying Alcohol Freely with CO2, Vitamin C, and Melatonin
with Matt Blackburn
Q&A: What the Anti PUFA Crowd Gets Wrong and Melatonin Dosing for Kids
with Matt Blackburn
What Body Temperature and Pulse Says About Your Metabolism with Jayton Miller
with Jayton Miller
Hydrogen Gas: Reduce Inflammation, Restore Redox Balance & Activates NRF2 (The Recovery Molecule)
with Hydrogen Gas
The Secret to Looking Younger is in Mushrooms (And Chocolate?) : 1417
with Baran Dilaver
Harvard Doctor: The Hidden Reason Behind Low Energy, Aging, and Cognitive Decline (And How to Fix It)
with Dr. Andrew Salzman
What if Your Brain Isn't Broken—It's Just NAD Depleted? A Deep Dive into NAD Supplements with Guest Dr. Andrew Salzman of Wonderfeel
with Dr. Andrew Salzman
NAD and NMN with Dr. Charles Brenner
with Dr. Charles Brenner
#207 - AMA #35: "Anti-Aging" Drugs — NAD+, metformin, & rapamycin
with Matt Kaeberlein