American Glutton
Perform with Dr. Andy Galpin
Huberman Lab
The Proof with Simon Hill
The Art of Manliness

Best Ways to Lose Weight

12 episodes

Evidence-based approaches to fat loss — from fasting and zone 2 cardio to cold exposure and metabolic tracking.

Evidence-based approaches to fat loss — from fasting and zone 2 cardio to cold exposure and metabolic tracking.

Episodes

1
American Glutton
Step by Step: Unlocking the Power of Walking with Ethan Suplee
American Glutton 2025-05-12

Actor Ethan Suplee and co-host Paige Dorian have a candid conversation about walking as an undervalued tool for fat loss, mental health, and daily movement. Ethan shares his per...

2
Perform with Dr. Andy Galpin
Dr. Herman Pontzer: How We Really Burn Calories & Lose Weight
Perform with Dr. Andy Galpin Dr. Herman Pontzer 2025-03-12

Dr. Herman Pontzer discusses his groundbreaking research on how humans really burn calories. Challenges conventional thinking about exercise and metabolism with evolutionary insights.

3
Huberman Lab
Essentials: Lose Fat With Science-Based Tools
Huberman Lab Andrew Huberman 2025-04-03

Andrew Huberman explains the neuroscience of fat loss, focusing on how the nervous system — not just calories in versus calories out — governs fat mobilization and oxidation. He...

4
Huberman Lab
Essentials: Effects of Fasting & Time Restricted Eating on Fat Loss & Health
Huberman Lab Andrew Huberman 2025-08-28

An 8-hour eating window improves metabolic health even without counting calories - your body shifts into cellular repair mode during extended fasts. Avoid food for 60 minutes af...

5
The Proof with Simon Hill
Science of zone 2 cardiovascular exercise | Inigo San Millan, PhD
The Proof with Simon Hill Inigo San Millan 2023-09-04

Simon Hill sits down with Dr. Inigo San Millan, an assistant professor at the University of Colorado and one of the world's foremost experts on metabolic health and exercise phy...

6
The Art of Manliness
Get Fit, Not Fried — The Benefits of Zone 2 Cardio
The Art of Manliness Alex Viada 2023-01-02

Brett McKay interviews hybrid athlete and coach Alex Viada on why most people skip zone 2 cardio entirely, jumping straight from rest to zone 3 and missing significant health an...

7
The Cabral Concept
2582: Find Your Proper Metabolic & Longevity Zone for Cardio (TT)
The Cabral Concept 2023-03-02

Dr. Stephen Cabral makes the case for adding cardiovascular training alongside weight training for longevity, acknowledging his own bias toward weights as a strength and conditi...

8
Episode 424: How Daily Walking Can Transform your Health
Naturally Nourished 2024-12-17

Integrative dietitian Allie Miller and co-host Becky Yu break down the latest research on why walking is one of the most underrated forms of exercise. They cover cardiovascular ...

9
The Model Health Show
TMHS 674: How to Utilize Cold Therapy to Burn Fat, Reduce Inflammation, & Build Confidence – with Dr. Susanna Søberg
The Model Health Show Susanna Soberg 2023-04-03

Shawn Stevenson interviews Dr. Susanna Soberg, one of the world's leading researchers on cold immersion therapy and brown adipose tissue. The conversation covers the science of ...

10
Ben Greenfield Life
Low-Carb Vs. High-Carb Battle — What's BETTER For Your Health & Metabolism: Fats or Sugar? with Dr. Eric Westman and Jay Feldman
Ben Greenfield Life Dr. Eric Westman & Jay Feldman 2025-09-11

Ben Greenfield moderates a debate between Dr. Eric Westman, a Duke University professor and founder of the Duke Keto Medicine Clinic, and Jay Feldman, a health coach and indepen...

11
Huberman Lab
Female-Specific Exercise & Nutrition for Health, Performance & Longevity | Dr. Stacy Sims
Huberman Lab Dr. Stacy Sims 2024-07-22

Dr. Stacy Sims, an exercise physiologist and nutrition scientist specializing in female-specific training, joins Huberman to discuss how women's physiology demands different app...

12
Wits & Weights | Evidence-Based Fitness & Nutrition for Lifters Over 40
Metabolism 101 (The Science Behind Fat Loss and Muscle Building) | Ep 421
Wits & Weights | Evidence-Based Fitness & Nutrition for Lifters Over 40 2026-01-02

Wits & Weights breaks down the science of metabolism for lifters over 40, covering how metabolic rate affects fat loss and muscle building, plus the role of time-restricted eating.

Related Research

Markers of clinical and mitochondrial adaptation in response to moderate intensity continuous training: A systematic review and meta-analysis
Vabishchevich V, Smith RT, Bittel AJ (2026)
Across 14 studies (n=184), moderate-intensity continuous training significantly increased mitochondrial volume density (p<0.00001) and VO2max (p<0.0001), with modest gains in citrate synthase and MFN2, confirming Zone 2-type exercise drives meaningful mitochondrial adaptation.
Intermittent fasting for weight management and metabolic health: An updated comprehensive umbrella review of health outcomes.
Hua Z, Yang S, Li J, et al. (2025)
Umbrella review of 40+ meta-analyses confirms intermittent fasting significantly reduces body weight, BMI, and fat mass with comparable metabolic improvements to continuous energy restriction.
Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis.
Ding D, Nguyen B, Nau T, et al. (2025)
A comprehensive Lancet meta-analysis confirms that higher daily step counts are associated with significantly lower risks of all-cause mortality, cardiovascular disease, cancer, and type 2 diabetes, with most benefits accruing by 8,000-10,000 steps per day.
Impact of different doses of cold water immersion on recovery from acute exercise-induced muscle damage
Wang H, et al. (2025)
Network meta-analysis of 55 RCTs found 10-15 min at 11-15°C optimal for reducing muscle soreness and damage markers.
High-intensity interval training and cardiorespiratory fitness in adults: An umbrella review of systematic reviews and meta-analyses.
Poon ET, Li H, Gibala MJ, et al. (2024)
HIIT produces large, consistent improvements in cardiorespiratory fitness across diverse adult populations, with effect sizes comparable to or greater than moderate-intensity continuous training.
The effects of the ketogenic diet for the management of type 2 diabetes mellitus: A systematic review and meta-analysis of recent studies.
Choy KYC, Louie JCY (2024)
Keto improved HDL and triglycerides in type 2 diabetes but showed no additional benefit for blood sugar control or weight loss compared to control diets over two years.