Huberman Lab

Using Caffeine to Optimize Mental & Physical Performance

Huberman Lab with Andrew Huberman 2022-12-05

Summary

Delay your morning coffee 90-120 minutes after waking to avoid afternoon crashes. Let your natural cortisol peak clear adenosine first, then use caffeine to extend alertness rather than create it.

Key Points

  • Delay caffeine 90-120 minutes after waking
  • Allow natural cortisol awakening response first
  • Let adenosine clear before blocking receptors
  • Get morning light exposure during the wait
  • May reduce afternoon energy crashes
  • May improve sleep quality

Key Moments

Caffeine

Caffeine is a powerful reinforcer: it makes you like the foods, drinks, and places you consume it

Over 90% of adults use caffeine daily. Beyond alertness, it reinforces preference for associated foods, cups, and environments.

"When caffeine is present in drinks and foods, we actively come to like those foods and drinks more than if caffeine were not contained in those foods and drinks."
Caffeine

Slow caffeine intake with food to extend alertness and avoid the afternoon crash

Ingesting caffeine with food slows absorption, extends its mood and alertness effects, and helps avoid the jitteriness and crash that come from rapid.

"One thing that works very well to maintain mood and alertness longer given a certain amount of caffeine intake is to slow its absorption."

Adenosine makes you tired by tapping into the ATP energy pathway

Caffeine blocks adenosine receptors that normally promote sleepiness.

"Adenosine makes us feel tired because of the way that it taps into the ATP pathway. Caffeine parks in the receptors for adenosine and blocks its pro-sleepy effects."

Delay caffeine 90-120 min after waking to avoid the afternoon crash

Drinking caffeine immediately upon waking feels good but causes an afternoon crash.

"Many people wake up in the morning, they drink caffeine within 10, 20, 30 minutes of waking, and they feel more alert naturally. But then in the early afternoon, they experience a dramatic dip."

Morning cortisol pulse + sunlight clears residual adenosine naturally without caffeine

The morning cortisol spike, boosted by bright light and physical activity, can clear residual adenosine on its own.

"That cortisol pulse increases mood, increases alertness, but it does one other important thing: through an indirect pathway, it can clear out any residual adenosine."

Related Interventions

In Playlists

Featured Experts