Key Takeaway
Meta-analysis of 8 studies (316 participants) found CBD has a substantial significant effect on reducing anxiety with a large effect size (Hedges' g = -0.92)
Summary
This systematic review and meta-analysis evaluated the therapeutic potential of CBD for anxiety disorders. Eight articles with 316 participants were included. The meta-analysis revealed a substantial significant impact of CBD on anxiety with a considerable effect size (Hedges' g = -0.92, 95% CI -1.80 to -0.04).
Methods
Systematic review and meta-analysis. Literature screened through June 2023 identifying 1,550 articles. Eight articles met criteria for meta-analysis with 316 total participants. Published in Psychiatry Research.
Key Results
CBD showed substantial significant impact on anxiety (Hedges' g = -0.92, 95% CI -1.80 to -0.04). Large effect size suggesting meaningful clinical benefit. Effects observed across different anxiety disorder subtypes.
Limitations
Small number of included studies (8). Total sample of only 316 participants. Wide confidence interval suggesting imprecision. Heterogeneity in CBD dosing and formulations. Variable study designs. Short follow-up periods.