Huberman Lab
FoundMyFitness
Ben Greenfield Life
The Proof with Simon Hill

Optimize Your Metabolism

12 episodes

Insulin sensitivity, blood sugar control, and metabolic health — the science of how your body burns fuel.

Insulin sensitivity, blood sugar control, and metabolic health — the science of how your body burns fuel.

Episodes

1
Huberman Lab
Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation | Dr. Casey Means
Huberman Lab Dr. Casey Means 2024-05-06

Dr. Casey Means, a Stanford-trained physician and author of 'Good Energy,' explains how metabolic dysfunction is the root cause of most chronic disease in America, with 93% of a...

2
FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep
FoundMyFitness Rhonda Patrick 2024-10-08

Ten bodyweight squats every 45 minutes beats a 30-minute walk for glucose control. Three daily 1-2 minute vigorous bursts correlate with 40-50% lower all-cause mortality. Finish...

3
Huberman Lab
Transform Your Metabolic Health & Longevity by Knowing Your Unique Biology | Dr. Michael Snyder
Huberman Lab Andrew Huberman 2025-09-08

Your glucose response to foods is highly individual - some spike to potatoes, others to grapes - making CGM data essential for personalized nutrition. Post-meal brisk walks (15-...

4
FoundMyFitness
#104 Dr. Ben Bikman: How To Reverse Insulin Resistance Through Diet, Exercise, & Sleep
FoundMyFitness Dr. Ben Bikman 2025-07-11

Your glucose can look normal while insulin is 2-4x elevated. Covers the physical signs that reveal insulin resistance (check your neck), why strength training beats cardio for m...

5
Ben Greenfield Life
Low-Carb Vs. High-Carb Battle — What's BETTER For Your Health & Metabolism: Fats or Sugar? with Dr. Eric Westman and Jay Feldman
Ben Greenfield Life Dr. Eric Westman & Jay Feldman 2025-09-11

Ben Greenfield moderates a debate between Dr. Eric Westman, a Duke University professor and founder of the Duke Keto Medicine Clinic, and Jay Feldman, a health coach and indepen...

6
The Proof with Simon Hill
Lactate: The Key to Metabolic Health, Mitochondria, and Longevity | Dr Iñigo San Millán
The Proof with Simon Hill Inigo San Millan 2025-10-06

In this follow-up conversation, Simon Hill and Dr. Inigo San Millan take a deep dive into lactate -- debunking the long-held myth that it is a toxic waste product and revealing ...

7
Huberman Lab
Using Red Light to Improve Metabolism & the Harmful Effects of LEDs | Dr. Glen Jeffery
Huberman Lab Andrew Huberman 2025-12-01

Red and infrared light (670nm) penetrates tissue to boost mitochondrial function, improving blood glucose, slowing retinal aging, and potentially rescuing vision in macular dege...

8
FoundMyFitness
#065 Dr. Satchin Panda on Circadian Insights into Exercise Timing, Melatonin Biology, and Peak Cognition
FoundMyFitness Dr. Satchin Panda 2021-07-05

Most people eat across 15+ hour windows, but restricting to 12 hours or less optimizes circadian function. Melatonin inhibits insulin, so eating near bedtime impairs glucose met...

9
The Dr. Layne Norton Podcast
Study Deep Dive: Does Aspartame Increase Insulin?
The Dr. Layne Norton Podcast Study Deep Dive 2026-02-02

Layne Norton, PhD, performs a detailed breakdown of a landmark 2025 systematic review and meta-analysis published in Advances in Nutrition examining whether aspartame affects gl...

10
The Neuro Experience
Zone 2 Training and Cancer Metabolism: The Science Behind Peak Metabolic Health | Dr Inigo San Millan
The Neuro Experience Inigo San Millan 2025-02-11

Dr. Inigo San Millan discusses his research connecting zone 2 training, mitochondrial function, and cancer metabolism. He explains how skeletal muscle acts as an endocrine organ...

11
Huberman Lab
How to Use Cold & Heat Exposure to Improve Your Health | Dr. Susanna Søberg
Huberman Lab Dr. Susanna Soberg 2023-05-15

Andrew Huberman interviews Dr. Susanna Soberg, the researcher behind the landmark Cell Reports Medicine study that established minimum thresholds for cold and heat exposure to b...

12
ZOE Science & Nutrition
We Need to Talk About Metabolism | Shawn Stevenson & Tim Spector
ZOE Science & Nutrition Shawn Stevenson 2025-12-30

Shawn Stevenson and Prof. Tim Spector discuss metabolism myths and facts, covering what really affects metabolic rate and how to optimize it for health and weight management.

Related Research

Markers of clinical and mitochondrial adaptation in response to moderate intensity continuous training: A systematic review and meta-analysis
Vabishchevich V, Smith RT, Bittel AJ (2026)
Across 14 studies (n=184), moderate-intensity continuous training significantly increased mitochondrial volume density (p<0.00001) and VO2max (p<0.0001), with modest gains in citrate synthase and MFN2, confirming Zone 2-type exercise drives meaningful mitochondrial adaptation.
Intermittent fasting for weight management and metabolic health: An updated comprehensive umbrella review of health outcomes.
Hua Z, Yang S, Li J, et al. (2025)
Umbrella review of 40+ meta-analyses confirms intermittent fasting significantly reduces body weight, BMI, and fat mass with comparable metabolic improvements to continuous energy restriction.
Non-Invasive Continuous Glucose Monitoring in Patients Without Diabetes: Use in Cardiovascular Prevention, A Systematic Review
Wilczek F, van der Stouwe JG, Petrasch G, Niederseer D (2025)
Systematic review finds CGM may guide lifestyle interventions for cardiovascular prevention in non-diabetics by revealing glucose variability patterns
Impact of different doses of cold water immersion on recovery from acute exercise-induced muscle damage
Wang H, et al. (2025)
Network meta-analysis of 55 RCTs found 10-15 min at 11-15°C optimal for reducing muscle soreness and damage markers.
Longer-term effects of intermittent fasting on body composition and cardiometabolic health in adults with overweight and obesity: A systematic review and meta-analysis.
Khalafi M, Maleki AH, Ehsanifar M, et al. (2025)
Meta-analysis of long-term IF studies (12+ weeks) shows sustained reductions in body weight, fat mass, and cardiometabolic markers in overweight/obese adults without excessive muscle loss.
What Is "Zone 2 Training"? Experts' Viewpoint on Definition, Training Methods, and Expected Adaptations
Multiple international experts (2025)
Expert consensus defines Zone 2 as just below LT1/VT1, with blood lactate ~1-2 mmol/L and HR at 70-80% max.