Huberman Lab

Using Red Light to Improve Metabolism & the Harmful Effects of LEDs | Dr. Glen Jeffery

Huberman Lab with Andrew Huberman 2025-12-01

Summary

Red and infrared light (670nm) penetrates tissue to boost mitochondrial function, improving blood glucose, slowing retinal aging, and potentially rescuing vision in macular degeneration. Meanwhile, blue-heavy LED light during sleep impairs cardiometabolic health. Replace LEDs with incandescent or halogen bulbs in the evening and prioritize darkness during sleep.

Key Points

  • Long-wavelength red and infrared light penetrates tissue to boost mitochondrial function, improving metabolism, blood glucose regulation, and aging processes
  • Red light stimulation improves aged mitochondrial function and reduces age-related photoreceptor loss in the retina
  • Short-wavelength light from LEDs can impair mitochondrial health and has been associated with serious health consequences during sleep
  • Using 670nm red light exposure can help offset retinal aging, preserve vision, and potentially rescue sight in age-related macular degeneration
  • Natural sunlight provides balanced full-spectrum wavelengths; incandescent and halogen bulbs offer better alternatives than LEDs for indoor environments
  • Light exposure during sleep significantly impairs cardiometabolic function, making darkness and warm light sources essential during evening hours
  • Incorporating plants, natural windows, and warm lighting indoors while limiting blue-heavy LED exposure supports mitochondrial and systemic health

Key Moments

Red and near-infrared light protects against LED and screen damage to mitochondria

Dr. Glenn Jeffrey's lab found that red, near-infrared, and infrared light can improve skin, eyesight, and blood sugar regulation by counteracting.

"Jeffrey's lab has discovered that certain wavelengths or colors of light can be used to improve your skin, your eyesight, even your blood sugar regulation and metabolism. Dr."

Red light makes mitochondria build more electron transport chain proteins

Long wavelength light increases electron transport chain proteins in mitochondria.

"Giving red light gets the train to run down the track faster. But then something detects the speed of that train and says, lay down more tracks. We need more tracks."

Red light on skin lowers blood sugar response to meals in humans

Shining red light on a small area of skin during a meal significantly reduced the blood glucose spike.

"Literally, blood sugar response is altered by shining red light on the skin."

Blue light raises blood glucose while red light lowers it, tested in bees and humans

In experiments, red light exposure reduced blood glucose rises after eating, while blue light caused glucose to spike much higher by slowing.

"We give them red light and their blood glucose does not go up as much. We give them blue light and their blood glucose goes very high."

Red light penetrates bone and skull, reaching the brain and inner ear

Long wavelength red light passes through bone surprisingly well.

"They were shining red light in the eye. And they say, we can see it in the ear. So it is absorbed by deoxygenated blood."

A burst of 670nm red light improved color vision thresholds in every subject

Subjects received a short burst of 670nm deep red light, then retook color vision tests.

"We then gave them a burst of red light to improve their mitochondria in cells that are very mitochondrial dependent, and we then brought them back and we found the threshold had changed."

Even dim red light at 1 mW/cm2 produces measurable biological effects

A researcher accidentally used nearly dead batteries and still got results.

"She was getting an effect close at one milliwatt per centimeter squared. That is low. That's dim red light."

Local red light triggers systemic effects via cytokine signaling throughout the body

Shining red light on one body part like the knee produces local effects within 1-2 hours, then triggers systemic changes as the signal spreads via.

"So if you shine the light on your kneecap, something will probably happen within one to two hours. At the kneecap."

Schools and care homes need infrared light: LEDs and IR-blocking windows starve cells

Modern environments with LED lighting and infrared-blocking windows deprive people of beneficial long-wavelength light.

"You're getting no infrared light. You've got infrared blocking windows. You've got LEDs. What happens when I wheel you into a park? You know you feel so much better."

Red light dramatically improved symptoms in a child with mitochondrial disease

A parent applied red light therapy to their child with mitochondrial disease.

"We were looking at simple metrics, which is how much they could open their eyelids. It's called ptosis, right? It couldn't open their eyes."

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