FoundMyFitness
Huberman Lab
The Tim Ferriss Show
Paul Saladino MD Podcast

Prevent Cognitive Decline

12 episodes

Protect your brain from Alzheimer's and dementia — exercise, nutrition, sleep, and emerging research.

Protect your brain from Alzheimer's and dementia — exercise, nutrition, sleep, and emerging research.

Episodes

1
FoundMyFitness
#079 Blood-Brain Barrier Dysfunction in Alzheimer's Disease and Dementia | Axel Montagne, Ph.D.
FoundMyFitness Dr. Axel Montagne 2023-02-28

Blood-brain barrier breakdown happens before cognitive decline and may be the real driver of dementia. APOE4 carriers face higher risk through vascular dysfunction, but aerobic ...

2
Huberman Lab
How to Improve Brain Health & Offset Neurodegeneration | Dr. Gary Steinberg
Huberman Lab Dr. Gary Steinberg 2024-05-20

Dr. Gary Steinberg, a neurosurgeon and professor of neurosciences at Stanford, discusses brain health, stroke, traumatic brain injury (TBI), concussion, and cutting-edge treatme...

3
The Tim Ferriss Show
#851: Dr. Tommy Wood — How to Future-Proof Your Brain from Dementia
The Tim Ferriss Show Dr. Tommy Wood 2026-01-28

Dr. Tommy Wood, associate professor of pediatrics and neuroscience at the University of Washington, discusses practical strategies for future-proofing the brain against dementia...

4
Paul Saladino MD Podcast
186. Dr. Tommy Wood: Tools to Keep Your Brain Healthy and Avoid Dementia
Paul Saladino MD Podcast Dr. Tommy Wood 2022-10-24

Dr. Tommy Wood makes his third appearance on Paul's podcast to cover brain health, dementia prevention, lipids, LDL cholesterol, continuous glucose monitors, and seed oils. As a...

5
FoundMyFitness
#043 Dr. Dale Bredesen on Preventing and Reversing Alzheimer's Disease
FoundMyFitness Dr. Dale Bredesen 2018-10-01

Dr. Dale Bredesen discusses his research on preventing and reversing Alzheimer's disease through identifying and addressing root causes including metabolic dysfunction, inflamma...

6
Dementia is Diabetes of the Brain: Metabolic Health and Cognitive Decline
High Intensity Health Mike Mutzel 2023-12-14

Dementia is Diabetes of the Brain: Metabolic Health and Cognitive Decline. The host explores evidence-based insights on this topic, covering practical protocols and the latest r...

7
Perform with Dr. Andy Galpin
Nutrition to Support Brain Health & Offset Brain Injuries
Perform with Dr. Andy Galpin Andy Galpin 2024-08-14

Dr. Andy Galpin discusses nutrition and supplementation strategies to reduce the risk of brain injury and enhance brain performance and long-term health. He explains what happen...

8
Perform with Dr. Andy Galpin
Dr. Tommy Wood: Enhancing Brain Performance & Preventing Dementia
Perform with Dr. Andy Galpin Dr. Tommy Wood 2025-02-12

Dr. Tommy Wood, a UK-trained M.D. with a Ph.D. in physiology and neuroscience and professor at the University of Washington, discusses how physical and mental challenges can enh...

9
Modern Wisdom
Dr Lisa Feldman Barrett - The New Science Of Emotions, Anxiety & Brain Health
Modern Wisdom Dr Lisa Feldman Barrett 2025-08-30

Lisa Feldman Barrett is a professor at Northeastern University, psychologist, and a neuroscientist. Why do we feel emotions? From happiness and joy to anger, anxiety, and sorrow...

10
Huberman Lab
Essentials: Food & Supplements for Brain Health & Cognitive Performance
Huberman Lab Andrew Huberman 2025-09-11

Three supplements with solid evidence for brain health: EPA omega-3s (1.5-3g daily) for neuronal membranes, creatine (5g daily) as brain fuel for mood and cognition, and choline...

11
ZOE Science & Nutrition
Recap: Tips to help prevent Alzheimer’s | Drs. Ayesha & Dean Sherzai
ZOE Science & Nutrition Drs. Ayesha & Dean Sherzai 2025-12-16

Drs. Ayesha & Dean Sherzai joins ZOE Science & Nutrition to discuss tips to help prevent alzheimer’s | drs. ayesha & dean sherzai. Key topics include protocols for cognitive enh...

12
FoundMyFitness
#102 Why Vitamin D Deficiency Accelerates Brain Aging
FoundMyFitness Rhonda Patrick 2025-05-21

Vitamin D supplementation cut dementia risk by 40% in a 12,000-person study. Learn why nearly 70% of Americans are deficient, how age and body fat tank your levels, and the bloo...

Related Research

Markers of clinical and mitochondrial adaptation in response to moderate intensity continuous training: A systematic review and meta-analysis
Vabishchevich V, Smith RT, Bittel AJ (2026)
Across 14 studies (n=184), moderate-intensity continuous training significantly increased mitochondrial volume density (p<0.00001) and VO2max (p<0.0001), with modest gains in citrate synthase and MFN2, confirming Zone 2-type exercise drives meaningful mitochondrial adaptation.
The Effect of Creatine Supplementation on Resistance Training-Based Changes to Body Composition: A Systematic Review and Meta-analysis.
Desai I, Wewege MA, Jones MD, et al. (2025)
Creatine supplementation during resistance training increased lean body mass by 1.14 kg, reduced body fat percentage by 0.88%, and reduced fat mass by 0.73 kg compared to training alone.
What Is "Zone 2 Training"? Experts' Viewpoint on Definition, Training Methods, and Expected Adaptations
Multiple international experts (2025)
Expert consensus defines Zone 2 as just below LT1/VT1, with blood lactate ~1-2 mmol/L and HR at 70-80% max.
Mindfulness enhances cognitive functioning: a meta-analysis of 111 randomized controlled trials.
Zainal NH, Newman MG (2024)
Largest meta-analysis to date (111 RCTs, n=9,538) found mindfulness has small-to-moderate effects on global cognition, executive attention, working memory, and processing speed.
A systematic review of ambient heat and sleep in a warming climate.
Chevance G, Minor K, Vielma C, et al. (2024)
Higher outdoor or indoor temperatures are consistently associated with degraded sleep quality and quantity worldwide, with limited evidence of fast human adaptation to heat.
Individual participant data systematic review and meta-analysis of randomised controlled trials assessing adult mindfulness-based programmes for mental health promotion in non-clinical settings.
Galante J, Friedrich C, et al. (2023)
IPD meta-analysis confirmed mindfulness-based programs reduce psychological distress at 1-6 months, with strongest effects for those with higher baseline distress.