The Model Health Show
Boundless Life
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Sawbones: A Marital Tour of Misguided Medicine

Intranasal Light Therapy

9 episodes C

Episodes covering intranasal light therapy — protocols, research, and expert discussions.

Delivering red or near-infrared light through the nasal cavity to target the brain, blood, and sinuses for cognitive enhancement and systemic benefits

Intranasal light therapy is a targeted form of photobiomodulation that delivers light through the nose, where thin tissue and rich blood supply allow penetration to the brain and systemic circulation. Early research shows promise for cognitive function, mood, and sleep quality, but evidence is still limited compared to transcranial or panel-based red light therapy.

An interesting addition to a biohacking stack, especially for cognitive focus. Devices are relatively affordable and the intervention is low-risk. Consider it experimental but promising - the mechanism is sound even if large-scale trials are lacking.

Science & Mechanisms

Mechanisms:

  • Red/NIR light (633-810nm) penetrates nasal mucosa
  • Reaches prefrontal cortex and limbic structures via cribriform plate
  • Irradiates blood passing through nasal capillaries (systemic effect)
  • Absorbed by cytochrome c oxidase, enhancing mitochondrial ATP production
  • May improve cerebral blood flow
  • Potential anti-inflammatory effects on sinuses

Why intranasal delivery:

  • Nasal tissue is thin (0.5-2mm) with minimal barrier
  • Rich capillary bed for blood irradiation
  • Direct pathway to brain via olfactory bulb region
  • Complements transcranial approaches (different target areas)

Key research:

  • Pilot studies show improved cognitive function in dementia patients
  • Enhanced memory and attention in healthy adults (small studies)
  • Improved sleep quality in some trials
  • Blood viscosity and flow improvements observed

Effect sizes:

  • Cognitive enhancement: Small (more research needed)
  • Sleep improvement: Small to moderate
  • Mood enhancement: Preliminary positive signals
  • Systemic blood effects: Under investigation

Limitations:

  • Most studies are small or pilot-scale
  • Optimal parameters (wavelength, power, duration) not established
  • Mechanism of brain effects still debated
  • Commercial device quality varies significantly

Episodes

1
The Model Health Show
The Truth About Red Light Therapy and Using Light as Medicine
The Model Health Show 2025-10-20

Shawn Stevenson delivers a solo masterclass on light therapy and photobiomodulation, presenting peer-reviewed evidence for four major applications of light as medicine: pain red...

2
Boundless Life
How To Use Low Level Light Therapy and Intranasal Light Therapy For Athletic Performance, Cognitive Enhancement & More.
Boundless Life Dr. Lew Lim 2015-10-10

Ben Greenfield interviews Dr. Lew Lim, inventor of the VieLight intranasal light therapy device and expert in photobiomodulation. Dr. Lim explains how low-level light therapy wo...

3
The Energy Code
The Final Red Light Report: Methylene Blue, Red Light, and the Future of Mitochondrial Health
The Energy Code 2025-08-21

Dr. Mike Belkowski presents the final episode of The Red Light Report before rebranding to The Energy Code, covering four recent photobiomodulation studies. He reviews a randomi...

4
Boundless Life
Sleep, Light, Alarms, Caffeine, Night Shifts, Naps, Sleeping Positions & More With Shawn Stevenson.
Boundless Life Shawn Stevenson 2016-05-04

Ben Greenfield interviews Shawn Stevenson, author of Sleep Smarter, about optimizing sleep quality through light exposure, caffeine management, and circadian rhythm alignment. S...

5
The Evolving Wellness Podcast with Sarah Kleiner Wellness
Unlocking Hope for Neurodegenerative Diseases: How Red Light Therapy is Changing Lives with Peter Adams
The Evolving Wellness Podcast with Sarah Kleiner Wellness Peter Adams 2023-08-30

Sarah Kleiner interviews Peter Adams, VP of Business Development at VieLight, about how intranasal and transcranial red light therapy is being used for neurodegenerative disease...

6
Sawbones: A Marital Tour of Misguided Medicine
Blue Light Therapy
Sawbones: A Marital Tour of Misguided Medicine 2021-03-23

Hosts Justin and Dr. Sydnee McElroy explore the history of chromotherapy and blue light therapy, tracing its origins to Augustus James Pleasanton, a Civil War-era brigadier gene...

7
What's That Rash?
Infrared, ultraviolet and LED therapy – can lights cure us?
What's That Rash? 2024-12-17

Hosts Tegan Taylor and Dr. Norman Swan walk through the electromagnetic spectrum from infrared to ultraviolet, examining the health claims around different colors of light. They...

8
Boundless Life
How To Blast The Brain With Energy by Using Red Light Therapy Headsets, Laser/LED Treatment For COVID, Instantly Shift the Brain Into A "Bliss" State & More
Boundless Life Dr. Lew Lim 2023-02-04

Ben Greenfield reunites with Dr. Lew Lim of VieLight for an updated discussion on brain photobiomodulation, covering major developments since their first interview over five yea...

9
Decoding Superhuman
Transcranial and Intranasal Photobiomodulation
Decoding Superhuman Dr. Lew Lim 2019-08-06

Boomer Anderson interviews Dr. Lew Lim, founder and CEO of VieLight, about the science of transcranial and intranasal photobiomodulation. Dr. Lim traces the field back to 1967 d...

Related Research

Photobiomodulation in the aging brain: a systematic review from animal models to humans.
Rodríguez-Fernández L, Zorzo C, Arias JL (2024)
Photobiomodulation demonstrates neuroprotective, anti-inflammatory, and mitochondrial-restoring effects in the aging brain, improving working memory, cognitive inhibition, and general cognition in both animal models and humans
Can transcranial photobiomodulation improve cognitive function? A systematic review of human studies.
Lee T, Ding Z, Chan AS (2022)
29 of 35 human studies (83%) found that transcranial photobiomodulation improved cognitive function, with strongest evidence in dementia and mild cognitive impairment
Pulsed Near Infrared Transcranial and Intranasal Photobiomodulation Significantly Modulates Neural Oscillations
Zomorrodi R, Loheswaran G, Pushparaj A, Bhardwaj R, Bhimani R (2020)
Intranasal and transcranial photobiomodulation modulates brain oscillations associated with cognitive function
Effects of Home Photobiomodulation Treatments on Cognitive and Behavioral Function, Cerebral Perfusion, and Resting-State Functional Connectivity in Patients with Dementia: A Pilot Trial.
Chao LL (2020)
Home-based transcranial and intranasal photobiomodulation improved cognitive function, reduced neuropsychiatric symptoms, and increased cerebral perfusion in dementia patients over 12 weeks
Significant Improvement in Cognition in Mild to Moderately Severe Dementia Cases Treated with Transcranial Plus Intranasal Photobiomodulation
Saltmarche AE, Naeser MA, Ho KF, Hamblin MR, Lim L (2018)
Combined transcranial and intranasal photobiomodulation improved cognitive function in dementia patients