Studies

Association between naturally occurring lithium in drinking water and suicide rates: systematic review and meta-analysis of ecological studies

Meta-analysis confirms inverse association between lithium in drinking water and suicide rates across multiple populations.

Memon A (2021)

Caveat emptor: Folate in unipolar depressive illness, a systematic review and meta-analysis

L-methylfolate supplementation shows promise as an adjunctive treatment for depression, particularly in patients with inadequate response to antidepressants.

Roberts E (2019)

Accelerated TMS for Depression: A systematic review and meta-analysis

Meta-analysis confirms accelerated TMS protocols are effective for depression with faster onset than traditional TMS.

Sonmez AI (2019)

Transcranial magnetic stimulation in anxiety and trauma-related disorders: A systematic review and meta-analysis

TMS shows promising results for anxiety disorders including GAD, panic disorder, and PTSD with various protocols.

Cirillo P (2020)

Stanford Neuromodulation Therapy (SNT): A Double-Blind Randomized Controlled Trial.

SAINT protocol achieved 79% remission rate in treatment-resistant depression with effects appearing within days.

Cole EJ (2022)

Research on the Intervention Effect of Vibroacoustic Therapy in the Treatment of Patients with Depression

Somatosensory music therapy (vibroacoustic) improved depressive symptoms, increased positive emotions, reduced negative emotions, and helped restore autonomic nervous system balance over 4 weeks.

Liu et al. (2024)

Muscle relaxation therapy for anxiety disorders: It works but how?

Comprehensive review confirms PMR effectively reduces anxiety symptoms, though the exact mechanisms (muscle tension vs cognitive) remain debated.

Conrad A (2007)

Efficacy of Eye Movement Desensitization and Reprocessing for Patients with Posttraumatic Stress Disorder: A Meta-Analysis of Randomized Controlled Trials

Meta-analysis of 26 RCTs found EMDR significantly reduces PTSD symptoms compared to controls, with effects maintained at follow-up.

Chen YR (2014)

A meta-analysis of the contribution of eye movements in processing emotional memories

Meta-analysis confirmed eye movements during memory recall reduce emotional intensity, supporting the working memory theory of EMDR's mechanism.

Lee CW (2013)

Autogenic training: A meta-analysis of clinical outcome studies

Meta-analysis of 60 studies found autogenic training produces medium-to-large effects for anxiety, depression, and functional disorders.

Stetter F (2002)

Autogenic training for stress and anxiety: a systematic review

Systematic review found autogenic training moderately effective for stress and anxiety reduction, though methodological quality of studies was variable.

Ernst E (2000)

Breathwork-Induced Psychedelic Experiences Modulate Neural Dynamics

Largest breathwork study to date found SOMA breathwork produces psychedelic-like neural changes, with increased brain complexity during breath holds similar to psilocybin effects.

Lewis-Healey E (2024)

[Effect of Autogenic Training for Stress Response: A Systematic Review and Meta-Analysis].

Systematic review and meta-analysis of 21 studies found autogenic training significantly reduces anxiety and depression while increasing heart rate variability in adults.

Seo E (2020)

Autogenic training to reduce anxiety in nursing students: randomized controlled trial.

Eight weeks of autogenic training significantly reduced both state and trait anxiety in nursing students compared to laughter therapy and no-intervention controls.

Kanji N (2006)

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